Mechanistic role of kinases in the regulation of mitochondrial fitness

Daniela Sorriento, Jessica Gambardella, Antonella Fiordelisi, Bruno Trimarco, Michele Ciccarelli, Guido Iaccarino, Gaetano Santulli

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Abstract

Mounting evidence indicates that mitochondria contain multiple phosphorylation substrates and that protein kinases translocate into mitochondria, suggesting that protein phosphorylation in this organelle could be fundamental for the regulation of its own function. Here we examine the mechanistic role of cellular kinases in the fine regulation of key mitochondrial activities, including mitochondrial quality control, fission/fusion processes, metabolism, and mitophagy.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages521-528
Number of pages8
DOIs
StatePublished - May 1 2017
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
Volume982
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Sorriento, D., Gambardella, J., Fiordelisi, A., Trimarco, B., Ciccarelli, M., Iaccarino, G., & Santulli, G. (2017). Mechanistic role of kinases in the regulation of mitochondrial fitness. In Advances in Experimental Medicine and Biology (pp. 521-528). (Advances in Experimental Medicine and Biology; Vol. 982). Springer New York LLC. https://doi.org/10.1007/978-3-319-55330-6_26