TY - JOUR
T1 - Maternal experiences of ethnic discrimination and child cardiometabolic outcomes in the Study of Latino Youth
AU - Slopen, Natalie
AU - Strizich, Garrett
AU - Hua, Simin
AU - Gallo, Linda C.
AU - Chae, David H.
AU - Priest, Naomi
AU - Gurka, Matthew J.
AU - Bangdiwala, Shrikant I.
AU - Bravin, Julia I.
AU - Chambers, Earle C.
AU - Daviglus, Martha L.
AU - Llabre, Maria M.
AU - Carnethon, Mercedes R.
AU - Isasi, Carmen R.
N1 - Funding Information:
The SOL Youth Study was supported by Grant Number R01HL102130 from the National Heart, Lung, and Blood Institute, United States. The children in SOL Youth are drawn from the study of adults: The Hispanic Community Health Study/Study of Latinos, which was supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina, United States (N01-HC65233), University of Miami, United States (N01-HC65234), Albert Einstein College of Medicine, United States (N01-HC65235), Northwestern University, United States (N01-HC65236), and San Diego State University, United States (N01-HC65237). N.S. was supported by a Research and Scholarship Award from the Graduate School, University of Maryland, United States and Grant P3022586 from the W. K. Kellogg Foundation. M.J.G. was supported by NHLBI grant R01HL120960.
Funding Information:
The SOL Youth Study was supported by Grant Number R01HL102130 from the National Heart, Lung, and Blood Institute , United States. The children in SOL Youth are drawn from the study of adults: The Hispanic Community Health Study/Study of Latinos, which was supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina , United States ( N01-HC65233 ), University of Miami , United States ( N01-HC65234 ), Albert Einstein College of Medicine , United States ( N01-HC65235 ), Northwestern University , United States ( N01-HC65236 ), and San Diego State University , United States ( N01-HC65237 ). N.S. was supported by a Research and Scholarship Award from the Graduate School, University of Maryland , United States and Grant P3022586 from the W. K. Kellogg Foundation. M.J.G. was supported by NHLBI grant R01HL120960 .
Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/6
Y1 - 2019/6
N2 - Purpose: Limited research has examined maternal experiences of racial/ethnic discrimination in relation to child cardiometabolic health. In this study, we investigated whether maternal experiences of ethnic discrimination were associated with cardiometabolic risk in Hispanic/Latino youth several years later. Methods: Our sample included 1146 youth (8–16 years)from the Study of Latino Youth (2012–2014), who were children of the Hispanic Community Health Study/Study of Latinos participants (2008–2011). We used regression models to examine the prospective associations between maternal report of ethnic discrimination in relation to her child's body mass index (BMI)z-score, metabolic syndrome score (MetS), and high sensitivity C-reactive protein (hsCRP)levels 2 years later. Results: Maternal ethnic discrimination was associated with youth hsCRP, but not BMI or MetS (P-values >.05). Adjusting for age, nativity, and national background, maternal ethnic discrimination was associated with higher (log)hsCRP levels (β = 0.18, 95% CI = 0.04 to 0.32)in children. This association was robust to adjustment for maternal and household characteristics (β = 0.17, 95% CI = 0.04 to 0.31), as well as maternal depression and maternal BMI. Conclusions: Maternal ethnic discrimination is associated with inflammation among Hispanic/Latino youth, and not BMI z-score or MetS. Studies are needed to address temporality and pathways.
AB - Purpose: Limited research has examined maternal experiences of racial/ethnic discrimination in relation to child cardiometabolic health. In this study, we investigated whether maternal experiences of ethnic discrimination were associated with cardiometabolic risk in Hispanic/Latino youth several years later. Methods: Our sample included 1146 youth (8–16 years)from the Study of Latino Youth (2012–2014), who were children of the Hispanic Community Health Study/Study of Latinos participants (2008–2011). We used regression models to examine the prospective associations between maternal report of ethnic discrimination in relation to her child's body mass index (BMI)z-score, metabolic syndrome score (MetS), and high sensitivity C-reactive protein (hsCRP)levels 2 years later. Results: Maternal ethnic discrimination was associated with youth hsCRP, but not BMI or MetS (P-values >.05). Adjusting for age, nativity, and national background, maternal ethnic discrimination was associated with higher (log)hsCRP levels (β = 0.18, 95% CI = 0.04 to 0.32)in children. This association was robust to adjustment for maternal and household characteristics (β = 0.17, 95% CI = 0.04 to 0.31), as well as maternal depression and maternal BMI. Conclusions: Maternal ethnic discrimination is associated with inflammation among Hispanic/Latino youth, and not BMI z-score or MetS. Studies are needed to address temporality and pathways.
KW - Cardiometabolic health
KW - Children
KW - Discrimination
KW - Study of Latino Youth
UR - http://www.scopus.com/inward/record.url?scp=85065022160&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85065022160&partnerID=8YFLogxK
U2 - 10.1016/j.annepidem.2019.03.011
DO - 10.1016/j.annepidem.2019.03.011
M3 - Article
C2 - 31060896
AN - SCOPUS:85065022160
SN - 1047-2797
VL - 34
SP - 52
EP - 57
JO - Annals of Epidemiology
JF - Annals of Epidemiology
ER -