Mapping the homolog of the human Rb1 gene to Chromosome 14 of higher primates

R. S. Verma, K. H. Ramesh, R. V. Samonte, R. A. Conte

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The RbI gene has been implicated with retinoblastoma and is located on human Chromosome (Chr) 13q14.2. A unique sequence human RbI cosmid DNA probe has been used to localize this region on apes' Chr 14 by the FISH technique. The conservation of the RbI gene in higher primates at the corresponding equivalent chromosome locus (14q14) of the human may serve as a phylogenetic marker to further trace the evolutionary pathway of human descent.

Original languageEnglish (US)
Pages (from-to)591-592
Number of pages2
JournalMammalian Genome
Volume7
Issue number8
DOIs
StatePublished - Jan 1 1996

ASJC Scopus subject areas

  • Genetics

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