Mapping of the MYCL2 processed gene to Xq22-23 and identification of an additional L MYC-related sequence in Xq27.2

E. Redolfi, A. Pizzuti, A. Di Bacco, L. Susani, T. Labella, M. Affer, C. Montagna, R. Reinbold, S. Mumm, P. Vezzoni, I. Zucchi

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

We report here the identification of a human genomic sequence from the q27.2 region of the X chromosome which shows a high homology to the L-MYC proto-oncogene. This sequence is not the MYCL2 homology, previously mapped to the long arm of the X chromosome at q22-qter by Morton et al., as we located the MYCL2-processed gene in Xq22-23, using a panel containing a combination of hybrid DNA carrying different portions of the human X chromosome. Based on computer analysis, the MYC-like sequence (MYCL3) is 98.2% identical to a portion of exon 3 of the MYCL1 gene and maps to the Xq27.2 region, between the DXS312 and DXS292 loci. Copyright (C) 1999 Federation of European Biochemical Societies.

Original languageEnglish (US)
Pages (from-to)273-277
Number of pages5
JournalFEBS Letters
Volume446
Issue number2-3
DOIs
StatePublished - Mar 12 1999
Externally publishedYes

Keywords

  • Gene mapping
  • MYC homology
  • Xq27

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

Fingerprint Dive into the research topics of 'Mapping of the MYCL2 processed gene to Xq22-23 and identification of an additional L MYC-related sequence in Xq27.2'. Together they form a unique fingerprint.

  • Cite this

    Redolfi, E., Pizzuti, A., Di Bacco, A., Susani, L., Labella, T., Affer, M., Montagna, C., Reinbold, R., Mumm, S., Vezzoni, P., & Zucchi, I. (1999). Mapping of the MYCL2 processed gene to Xq22-23 and identification of an additional L MYC-related sequence in Xq27.2. FEBS Letters, 446(2-3), 273-277. https://doi.org/10.1016/S0014-5793(99)00243-4