Abstract
Manganese (Mn; atomic no. 25, weight = 54.94 g/mol, density = 7.43 at 20°C) is a transitional metal (Group VIIa), isolated in 1774, by the Swedish chemist Scheele. Mn is the 12th most abundant element in the earth's crust, naturally present in rocks, soil, water, and food. Mn is known to be an essential trace element for animals since 1931, required for normal mammalian physiological processes, such as bone growth, development of cartilage and connective tissues, reproductive, neuronal, immune, and antioxidant functions. It can exist in 11 oxidation states from -3 to +7, being the normally encountered valences +2 (the most common form in nature), +4 (in dioxide Mn) and +7 (in permanganate ion).
| Original language | English (US) |
|---|---|
| Title of host publication | Biometals in Neurodegenerative Diseases |
| Subtitle of host publication | Mechanisms and Therapeutics |
| Publisher | Elsevier Inc. |
| Pages | 117-151 |
| Number of pages | 35 |
| ISBN (Electronic) | 9780128045633 |
| ISBN (Print) | 9780128045626 |
| DOIs | |
| State | Published - Apr 28 2017 |
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Keywords
- Biokinetics
- Homeostatic control
- Manganese
- Metabolic functions
- Neurodegeneration
ASJC Scopus subject areas
- Medicine(all)
- Neuroscience(all)
Cite this
Manganese and Neurodegeneration. / Marques dos Santos, Dinamene; Aschner, Michael; Marreilha dos Santos, Ana P.
Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics. Elsevier Inc., 2017. p. 117-151.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Manganese and Neurodegeneration
AU - Marques dos Santos, Dinamene
AU - Aschner, Michael
AU - Marreilha dos Santos, Ana P.
PY - 2017/4/28
Y1 - 2017/4/28
N2 - Manganese (Mn; atomic no. 25, weight = 54.94 g/mol, density = 7.43 at 20°C) is a transitional metal (Group VIIa), isolated in 1774, by the Swedish chemist Scheele. Mn is the 12th most abundant element in the earth's crust, naturally present in rocks, soil, water, and food. Mn is known to be an essential trace element for animals since 1931, required for normal mammalian physiological processes, such as bone growth, development of cartilage and connective tissues, reproductive, neuronal, immune, and antioxidant functions. It can exist in 11 oxidation states from -3 to +7, being the normally encountered valences +2 (the most common form in nature), +4 (in dioxide Mn) and +7 (in permanganate ion).
AB - Manganese (Mn; atomic no. 25, weight = 54.94 g/mol, density = 7.43 at 20°C) is a transitional metal (Group VIIa), isolated in 1774, by the Swedish chemist Scheele. Mn is the 12th most abundant element in the earth's crust, naturally present in rocks, soil, water, and food. Mn is known to be an essential trace element for animals since 1931, required for normal mammalian physiological processes, such as bone growth, development of cartilage and connective tissues, reproductive, neuronal, immune, and antioxidant functions. It can exist in 11 oxidation states from -3 to +7, being the normally encountered valences +2 (the most common form in nature), +4 (in dioxide Mn) and +7 (in permanganate ion).
KW - Biokinetics
KW - Homeostatic control
KW - Manganese
KW - Metabolic functions
KW - Neurodegeneration
UR - http://www.scopus.com/inward/record.url?scp=85040581853&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85040581853&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-804562-6.00008-7
DO - 10.1016/B978-0-12-804562-6.00008-7
M3 - Chapter
AN - SCOPUS:85040581853
SN - 9780128045626
SP - 117
EP - 151
BT - Biometals in Neurodegenerative Diseases
PB - Elsevier Inc.
ER -