Mandibular dimensions in children with obstructive sleep apnea syndrome

Patricia H. Schiffman, Nathania K. Rubin, Troy Dominguez, Soroosh Mahboubi, Jayaram K. Udupa, Anne R. O'Donnell, Joseph M. McDonough, Greg Maislin, Richard J. Schwab, Raanan Arens

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Objective: We hypothesized that mandibular size may play a role in the etiology of obstructive sleep apnea syndrome (OSAS) in children, since a smaller mandible may reduce airway size. We used magnetic resonance imaging to determine the mandible dimensions of children with OSAS. Design: Case control study. Setting: Tertiary-care pediatric hospital. Participants: Twenty-four subjects (mean age 4.9 ± 1.7 years) with mild to moderate OSAS (Apnea Index 3.5 ± 5.1), and 24 matched controls (mean age 4.9 ± 1.8 years). Intervention: Magnetic resonance imaging of the upper airway under sedation. Measurements: Eight measurements were obtained from a 3-dimensional segmentation of the mandible using 3DVIEWNIX software. Measurements included length, height, width, midsymphysis menti angle, angle of mandible, enclosure area, surface area, and volume. Descriptive comparisons using Student t test and multivariate analyses of variance were performed. Results: Individual measurement comparisons revealed no significant differences between groups. Multivariate analysis showed a lower bound of a 95% confidence interval for an effect size measure for "general mandibular size," including all 6 linear, the area, and the volume measurements, to be -0.25. Conclusion: Our study shows that a smaller mandible is not a feature in children with OSAS who do not have apparent craniofacial abnormalities.

Original languageEnglish (US)
Pages (from-to)959-965
Number of pages7
Issue number5
StatePublished - Aug 1 2004
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)


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