Abstract
The development of hyponatremia represents an ominous event in the progression of cirrhosis to end-stage liver disease. It usually develops in those with refractory ascites and is a manifestation of the non-osmotic release of arginine vasopressin (AVP). In the hospitalized cirrhotic patient, hyponatremia is associated with increased disease severity and mortality. In this article, we review the pathophysiology of hyponatremia, its clinical implications, evaluation, and treatment.
Original language | English (US) |
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Pages (from-to) | S8-S17 |
Journal | Journal of hospital medicine |
Volume | 5 |
Issue number | SUPPL. 3 |
DOIs | |
State | Published - Jul 2010 |
Externally published | Yes |
Keywords
- Cirrhosis
- Common electrolyte disorder
- Hyponatremia
- Liver failure
- Portal hypertension
ASJC Scopus subject areas
- Leadership and Management
- Internal Medicine
- Fundamentals and skills
- Health Policy
- Care Planning
- Assessment and Diagnosis