Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour

Haiying Cheng, David E. Geist, May Piperdi, Renu Virk, Bilal Piperdi

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A 62-year-old woman with a pre-existing psoriasis was treated with oral imatinib (400 mg/day) for a metastatic gastrointestinal stromal tumour. Within 4 weeks of starting therapy, she developed a guttate psoriasis flare. The eruption markedly improved within 2 weeks following cessation of imatinib. However, it recurred when imatinib was recommenced. She has been able to continue on imatinib (400 mg/day) with low-dose oral methotrexate (12.5 mg/week) controlling the psoriasis.

Original languageEnglish (US)
Pages (from-to)41-43
Number of pages3
JournalAustralasian Journal of Dermatology
Volume50
Issue number1
DOIs
StatePublished - Feb 2009
Externally publishedYes

Fingerprint

Gastrointestinal Stromal Tumors
Psoriasis
Methotrexate
Imatinib Mesylate
Therapeutics

Keywords

  • Methotrexate
  • Tyrosine kinase inhibitors

ASJC Scopus subject areas

  • Dermatology

Cite this

Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour. / Cheng, Haiying; Geist, David E.; Piperdi, May; Virk, Renu; Piperdi, Bilal.

In: Australasian Journal of Dermatology, Vol. 50, No. 1, 02.2009, p. 41-43.

Research output: Contribution to journalArticle

@article{9f5a87bf4ce34d9b8401dd009bc7d406,
title = "Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour",
abstract = "A 62-year-old woman with a pre-existing psoriasis was treated with oral imatinib (400 mg/day) for a metastatic gastrointestinal stromal tumour. Within 4 weeks of starting therapy, she developed a guttate psoriasis flare. The eruption markedly improved within 2 weeks following cessation of imatinib. However, it recurred when imatinib was recommenced. She has been able to continue on imatinib (400 mg/day) with low-dose oral methotrexate (12.5 mg/week) controlling the psoriasis.",
keywords = "Methotrexate, Tyrosine kinase inhibitors",
author = "Haiying Cheng and Geist, {David E.} and May Piperdi and Renu Virk and Bilal Piperdi",
year = "2009",
month = "2",
doi = "10.1111/j.1440-0960.2008.00495.x",
language = "English (US)",
volume = "50",
pages = "41--43",
journal = "Australasian Journal of Dermatology",
issn = "0004-8380",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour

AU - Cheng, Haiying

AU - Geist, David E.

AU - Piperdi, May

AU - Virk, Renu

AU - Piperdi, Bilal

PY - 2009/2

Y1 - 2009/2

N2 - A 62-year-old woman with a pre-existing psoriasis was treated with oral imatinib (400 mg/day) for a metastatic gastrointestinal stromal tumour. Within 4 weeks of starting therapy, she developed a guttate psoriasis flare. The eruption markedly improved within 2 weeks following cessation of imatinib. However, it recurred when imatinib was recommenced. She has been able to continue on imatinib (400 mg/day) with low-dose oral methotrexate (12.5 mg/week) controlling the psoriasis.

AB - A 62-year-old woman with a pre-existing psoriasis was treated with oral imatinib (400 mg/day) for a metastatic gastrointestinal stromal tumour. Within 4 weeks of starting therapy, she developed a guttate psoriasis flare. The eruption markedly improved within 2 weeks following cessation of imatinib. However, it recurred when imatinib was recommenced. She has been able to continue on imatinib (400 mg/day) with low-dose oral methotrexate (12.5 mg/week) controlling the psoriasis.

KW - Methotrexate

KW - Tyrosine kinase inhibitors

UR - http://www.scopus.com/inward/record.url?scp=58249096084&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58249096084&partnerID=8YFLogxK

U2 - 10.1111/j.1440-0960.2008.00495.x

DO - 10.1111/j.1440-0960.2008.00495.x

M3 - Article

C2 - 19178491

AN - SCOPUS:58249096084

VL - 50

SP - 41

EP - 43

JO - Australasian Journal of Dermatology

JF - Australasian Journal of Dermatology

SN - 0004-8380

IS - 1

ER -