Management of gallstones and its related complications

P. Portincasa, A. Di Ciaula, O. De Bari, G. Garruti, V. O. Palmieri, David Q.H. Wang

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

The majority of gallstone patients remain asymptomatic; however, interest toward the gallstone disease is continuing because of the high worldwide prevalence and management costs and the development of gallstone symptoms and complications. For cholesterol gallstone disease, moreover, a strong link exists between this disease and highly prevalent metabolic disorders such as obesity, dyslipidemia, type 2 diabetes, hyperinsulinemia, hypertriglyceridemia and the metabolic syndrome. Information on the natural history as well as the diagnostic, surgical (mainly laparoscopic cholecystectomy) and medical tools available to facilitate adequate management of cholelithiasis and its complications are, therefore, crucial to prevent the negative outcomes of gallstone disease. Moreover, some risk factors for gallstone disease are modifiable and some preventive strategies have become necessary to reduce the onset and the severity of complications.

Original languageEnglish (US)
Pages (from-to)93-112
Number of pages20
JournalExpert Review of Gastroenterology and Hepatology
Volume10
Issue number1
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

Fingerprint

Gallstones
Cholelithiasis
Hypertriglyceridemia
Laparoscopic Cholecystectomy
Hyperinsulinism
Dyslipidemias
Natural History
Type 2 Diabetes Mellitus
Obesity
Cholesterol
Costs and Cost Analysis

Keywords

  • Cholecystectomy
  • Cholecystitis
  • Choledocholithiasis
  • Complications
  • Gallbladder cancer
  • gallstones
  • Oral litholysis
  • Prevention
  • Risk factors

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Management of gallstones and its related complications. / Portincasa, P.; Di Ciaula, A.; De Bari, O.; Garruti, G.; Palmieri, V. O.; Wang, David Q.H.

In: Expert Review of Gastroenterology and Hepatology, Vol. 10, No. 1, 01.01.2016, p. 93-112.

Research output: Contribution to journalReview article

Portincasa, P, Di Ciaula, A, De Bari, O, Garruti, G, Palmieri, VO & Wang, DQH 2016, 'Management of gallstones and its related complications', Expert Review of Gastroenterology and Hepatology, vol. 10, no. 1, pp. 93-112. https://doi.org/10.1586/17474124.2016.1109445
Portincasa, P. ; Di Ciaula, A. ; De Bari, O. ; Garruti, G. ; Palmieri, V. O. ; Wang, David Q.H. / Management of gallstones and its related complications. In: Expert Review of Gastroenterology and Hepatology. 2016 ; Vol. 10, No. 1. pp. 93-112.
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