Malaria var gene expression: Keeping up with the neighbors

Kami Kim

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations

Abstract

Plasmodium falciparum PfEMP1 is a malaria virulence protein whose expression is epigenetically regulated. The parasite's ability to express exclusively only one of the sixty var genes that encode PfEMP1 is essential for disease pathogenesis. Two recent papers identify key molecular players in determining whether a var gene is active or silenced (Volz et al., 2012; Zhang et al., 2011).

Original languageEnglish (US)
Pages (from-to)1-2
Number of pages2
JournalCell Host and Microbe
Volume11
Issue number1
DOIs
StatePublished - Jan 19 2012

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Virology

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