Major and minor electrocardiographic abnormalities and their association with underlying cardiovascular disease and risk factors in Hispanics/Latinos (from the Hispanic Community Health Study/Study of Latinos)

Pablo Denes, Daniel B. Garside, Donald Lloyd-Jones, Natalia Gouskova, Elsayed Z. Soliman, Robert J Ostfeld, Zhu Ming Zhang, Alvaro Camacho, Ronald Prineas, Leopoldo Raij, Martha L. Daviglus

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Abstract

The association of electrocardiographic (ECG) abnormalities with cardiovascular disease and risk factors has been extensively studied in whites and African-Americans. Comparable data have not been reported in Hispanics/Latinos. The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a multicenter, community-based, prospective cohort study of men and women of diverse backgrounds aged 18 to 74 years who self-identified as Hispanic/Latinos. Participants (n = 16,415) enrolled from March 2008 to June 2011. We describe the prevalence of minor and major ECG abnormalities and examined their cross-sectional associations with cardiovascular disease and risk factors. The Minnesota code criteria were used to define minor and major ECG abnormalities. Previous cardiovascular disease and risk factors were based on data obtained at baseline examination. Significant differences in prevalent ECG findings were found between men and women. Major ECG abnormalities were present in 9.2% (95% confidence interval 8.3 to 10.1) of men and 6.6% (95% confidence interval 5.8 to 7.3) of women (p <0.0001). The odds of having major ECG abnormalities significantly increased with age, presence of ≥3 cardiovascular risk factors, and prevalent cardiovascular disease, in both men and women. Significant differences in major ECG abnormalities were found among the varying groups; Puerto Ricans and Dominicans had more major abnormalities compared with Mexican men and women. In conclusion, in a large cohort of Hispanic/Latino men and women, prevalence of major abnormalities was low, yet strong associations of major ECG abnormalities with cardiovascular disease and risk factors were observed in both men and women.

Original languageEnglish (US)
Pages (from-to)1667-1675
Number of pages9
JournalAmerican Journal of Cardiology
Volume112
Issue number10
DOIs
StatePublished - Nov 15 2013

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Hispanic Americans
Cardiovascular Diseases
Health
Confidence Intervals
African Americans
Cohort Studies
Prospective Studies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Major and minor electrocardiographic abnormalities and their association with underlying cardiovascular disease and risk factors in Hispanics/Latinos (from the Hispanic Community Health Study/Study of Latinos). / Denes, Pablo; Garside, Daniel B.; Lloyd-Jones, Donald; Gouskova, Natalia; Soliman, Elsayed Z.; Ostfeld, Robert J; Zhang, Zhu Ming; Camacho, Alvaro; Prineas, Ronald; Raij, Leopoldo; Daviglus, Martha L.

In: American Journal of Cardiology, Vol. 112, No. 10, 15.11.2013, p. 1667-1675.

Research output: Contribution to journalArticle

Denes, Pablo ; Garside, Daniel B. ; Lloyd-Jones, Donald ; Gouskova, Natalia ; Soliman, Elsayed Z. ; Ostfeld, Robert J ; Zhang, Zhu Ming ; Camacho, Alvaro ; Prineas, Ronald ; Raij, Leopoldo ; Daviglus, Martha L. / Major and minor electrocardiographic abnormalities and their association with underlying cardiovascular disease and risk factors in Hispanics/Latinos (from the Hispanic Community Health Study/Study of Latinos). In: American Journal of Cardiology. 2013 ; Vol. 112, No. 10. pp. 1667-1675.
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AU - Lloyd-Jones, Donald

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AU - Soliman, Elsayed Z.

AU - Ostfeld, Robert J

AU - Zhang, Zhu Ming

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AU - Daviglus, Martha L.

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