Macaque-to-baboon cardiac transplantation: Model of choice for xenotransplantation in humans

R. E. Michler; W. W. Socha; C. C. Marboe; C. R. Smith; K. Reemtsma; J. Moor-Jankowski; E. A. Rose

Macaque-to-baboon cardiac transplantation: Model of choice for xenotransplantation in humans

R. E. Michler, W. W. Socha, C. C. Marboe, C. R. Smith, K. Reemtsma, J. Moor-Jankowski, E. A. Rose

Research output: Contribution to journal › Article › peer-review

Abstract

In summary, human-type and simian-type blood group analysis documents the immunologic and genetic proximity of the macaque and baboon as well as the anthropoid ape and human. It also suggests that the species-specific barrier between macaque and baboon is comparable to that observed between chimpanzee and human. Therefore, we propose that the readily available Old World monkey with its humanlike anatomy and physiology is the model of choice for the study of xenotransplantation in humans.

Original language	English (US)
Pages (from-to)	327-328
Number of pages	2
Journal	Transplantation proceedings
Volume	20
Issue number	1 SUPPL. 1
State	Published - 1988
Externally published	Yes

ASJC Scopus subject areas

Surgery
Transplantation

Cite this

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abstract = "In summary, human-type and simian-type blood group analysis documents the immunologic and genetic proximity of the macaque and baboon as well as the anthropoid ape and human. It also suggests that the species-specific barrier between macaque and baboon is comparable to that observed between chimpanzee and human. Therefore, we propose that the readily available Old World monkey with its humanlike anatomy and physiology is the model of choice for the study of xenotransplantation in humans.",

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AU - Michler, R. E.

AU - Socha, W. W.

AU - Marboe, C. C.

AU - Smith, C. R.

AU - Reemtsma, K.

AU - Moor-Jankowski, J.

AU - Rose, E. A.

PY - 1988

Y1 - 1988

N2 - In summary, human-type and simian-type blood group analysis documents the immunologic and genetic proximity of the macaque and baboon as well as the anthropoid ape and human. It also suggests that the species-specific barrier between macaque and baboon is comparable to that observed between chimpanzee and human. Therefore, we propose that the readily available Old World monkey with its humanlike anatomy and physiology is the model of choice for the study of xenotransplantation in humans.

AB - In summary, human-type and simian-type blood group analysis documents the immunologic and genetic proximity of the macaque and baboon as well as the anthropoid ape and human. It also suggests that the species-specific barrier between macaque and baboon is comparable to that observed between chimpanzee and human. Therefore, we propose that the readily available Old World monkey with its humanlike anatomy and physiology is the model of choice for the study of xenotransplantation in humans.

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ER -

Macaque-to-baboon cardiac transplantation: Model of choice for xenotransplantation in humans

Abstract

ASJC Scopus subject areas

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