Lung nodules and masses after cardiac transplantation

Linda B. Haramati, Larry L. Schulman, John H M Austin

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Single or multiple lung nodules or masses were noted at chest radiography in 25 (9.7%) of 257 patients after cardiac transplantation. Two episodes occurred in each of three patients, for a total of 28 (10.9%) episodes in the 257 patients within the first 18 months after transplantation (transplantation performed between July 1987 and December 1990). Bronchoscopy, percutaneous needle biopsy, and open lung biopsy were performed as clinically warranted to establish a diagnosis. Infection was found in 21 instances (8.2%) in 18 patients. The most frequent pathogens were Aspergillus (n = 9 [3.5%]) and Nocardia (n = 7 [2.7%]). Aspergillus was hospital acquired in eight (89%) of nine patients and had a right-sided predominance (20 [74%] of 27 lesions). The nodules or masses appeared a median of 2 months after transplantation for Aspergillus (range, 0.5-12 months) and 5 months for Nocardia (range, 1-10 months). B cell lymphoma manifested as numerous nodules in two patients (0.8%). Although a variety of causes were found for post-cardiac transplantation nodules or masses, the majority (75%) were infectious.

Original languageEnglish (US)
Pages (from-to)491-497
Number of pages7
JournalRadiology
Volume188
Issue number2
StatePublished - Aug 1993

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Heart Transplantation
Lung
Aspergillus
Nocardia
Transplantation
Needle Biopsy
Bronchoscopy
B-Cell Lymphoma
Radiography
Thorax
Biopsy
Infection

Keywords

  • Aspergillosis, 60.2056
  • Heart, transplantation, 51.459
  • Lung, effects of drugs on, 60.469,60.649
  • Lung, infection, 60.2014, 60.2056, 60.2066, 60.2075
  • Lung, nodule, 60.458
  • Lymphoma, 60.34
  • Nocardia, 60.2014

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Haramati, L. B., Schulman, L. L., & Austin, J. H. M. (1993). Lung nodules and masses after cardiac transplantation. Radiology, 188(2), 491-497.

Lung nodules and masses after cardiac transplantation. / Haramati, Linda B.; Schulman, Larry L.; Austin, John H M.

In: Radiology, Vol. 188, No. 2, 08.1993, p. 491-497.

Research output: Contribution to journalArticle

Haramati, LB, Schulman, LL & Austin, JHM 1993, 'Lung nodules and masses after cardiac transplantation', Radiology, vol. 188, no. 2, pp. 491-497.
Haramati LB, Schulman LL, Austin JHM. Lung nodules and masses after cardiac transplantation. Radiology. 1993 Aug;188(2):491-497.
Haramati, Linda B. ; Schulman, Larry L. ; Austin, John H M. / Lung nodules and masses after cardiac transplantation. In: Radiology. 1993 ; Vol. 188, No. 2. pp. 491-497.
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