Low-level lead exposure and cognitive development in early childhood

Alan L. Mendelsohn; Benard P. Dreyer; Arthur H. Fierman; Carolyn M. Rosen; Lori A. Legano; Hillary A. Kruger; Sylvia W. Lim; Susan Barasch; Loretta Au; Cheryl D. Courtlandt

doi:10.1097/00004703-199912000-00004

Low-level lead exposure and cognitive development in early childhood

Alan L. Mendelsohn, Benard P. Dreyer, Arthur H. Fierman, Carolyn M. Rosen, Lori A. Legano, Hillary A. Kruger, Sylvia W. Lim, Susan Barasch, Loretta Au, Cheryl D. Courtlandt

Pediatrics

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

The authors studied toddlers with low-level lead exposure to determine whether adverse developmental effects were evident. The study sample consisted of a cohort of 68 children aged 12 to 36 months who had blood lead levels lower than 25 μg/dL on a routine screening in a large urban public hospital clinic. Children with blood lead levels between 10 and 24.9 μg/dL had a mean Mental Developmental Index (Bayley Scales of Infant Development, Second Edition) score that was 6.3 points lower than that of children with blood lead levels between 0 and 9.9 μg/dL (95% confidence interval: 0.6, 11.9). After adjusting for confounders, the difference was 6.2 points (95% confidence interval: 1.7, 10.8). Pediatricians and public health entities should continue in their efforts to reduce the lead burden through environmental control and ongoing surveillance. J Dev Behav Pediatr 20:425-431, 1999. Index terms: preschool children, lead, cognitive development.

Original language	English (US)
Pages (from-to)	425-431
Number of pages	7
Journal	Journal of Developmental and Behavioral Pediatrics
Volume	20
Issue number	6
DOIs	https://doi.org/10.1097/00004703-199912000-00004
State	Published - Dec 1999

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental and Educational Psychology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/00004703-199912000-00004

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title = "Low-level lead exposure and cognitive development in early childhood",

abstract = "The authors studied toddlers with low-level lead exposure to determine whether adverse developmental effects were evident. The study sample consisted of a cohort of 68 children aged 12 to 36 months who had blood lead levels lower than 25 μg/dL on a routine screening in a large urban public hospital clinic. Children with blood lead levels between 10 and 24.9 μg/dL had a mean Mental Developmental Index (Bayley Scales of Infant Development, Second Edition) score that was 6.3 points lower than that of children with blood lead levels between 0 and 9.9 μg/dL (95% confidence interval: 0.6, 11.9). After adjusting for confounders, the difference was 6.2 points (95% confidence interval: 1.7, 10.8). Pediatricians and public health entities should continue in their efforts to reduce the lead burden through environmental control and ongoing surveillance. J Dev Behav Pediatr 20:425-431, 1999. Index terms: preschool children, lead, cognitive development.",

author = "Mendelsohn, {Alan L.} and Dreyer, {Benard P.} and Fierman, {Arthur H.} and Rosen, {Carolyn M.} and Legano, {Lori A.} and Kruger, {Hillary A.} and Lim, {Sylvia W.} and Susan Barasch and Loretta Au and Courtlandt, {Cheryl D.}",

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AU - Mendelsohn, Alan L.

AU - Dreyer, Benard P.

AU - Fierman, Arthur H.

AU - Rosen, Carolyn M.

AU - Legano, Lori A.

AU - Kruger, Hillary A.

AU - Lim, Sylvia W.

AU - Barasch, Susan

AU - Au, Loretta

AU - Courtlandt, Cheryl D.

PY - 1999/12

Y1 - 1999/12

N2 - The authors studied toddlers with low-level lead exposure to determine whether adverse developmental effects were evident. The study sample consisted of a cohort of 68 children aged 12 to 36 months who had blood lead levels lower than 25 μg/dL on a routine screening in a large urban public hospital clinic. Children with blood lead levels between 10 and 24.9 μg/dL had a mean Mental Developmental Index (Bayley Scales of Infant Development, Second Edition) score that was 6.3 points lower than that of children with blood lead levels between 0 and 9.9 μg/dL (95% confidence interval: 0.6, 11.9). After adjusting for confounders, the difference was 6.2 points (95% confidence interval: 1.7, 10.8). Pediatricians and public health entities should continue in their efforts to reduce the lead burden through environmental control and ongoing surveillance. J Dev Behav Pediatr 20:425-431, 1999. Index terms: preschool children, lead, cognitive development.

AB - The authors studied toddlers with low-level lead exposure to determine whether adverse developmental effects were evident. The study sample consisted of a cohort of 68 children aged 12 to 36 months who had blood lead levels lower than 25 μg/dL on a routine screening in a large urban public hospital clinic. Children with blood lead levels between 10 and 24.9 μg/dL had a mean Mental Developmental Index (Bayley Scales of Infant Development, Second Edition) score that was 6.3 points lower than that of children with blood lead levels between 0 and 9.9 μg/dL (95% confidence interval: 0.6, 11.9). After adjusting for confounders, the difference was 6.2 points (95% confidence interval: 1.7, 10.8). Pediatricians and public health entities should continue in their efforts to reduce the lead burden through environmental control and ongoing surveillance. J Dev Behav Pediatr 20:425-431, 1999. Index terms: preschool children, lead, cognitive development.

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Low-level lead exposure and cognitive development in early childhood

Abstract

ASJC Scopus subject areas

UN SDGs

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