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Loss of folic acid exporter function with markedly augmented folate accumulation in lipophilic antifolate-resistant mammalian cells
Yehuda G. Assaraf, I. David Goldman
Oncology
Research output
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Article
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peer-review
52
Scopus citations
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Dive into the research topics of 'Loss of folic acid exporter function with markedly augmented folate accumulation in lipophilic antifolate-resistant mammalian cells'. Together they form a unique fingerprint.
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Chemical Compounds
Folate
86%
Folic Acid
84%
Mammalian Cell
75%
Methotrexate
64%
Energy
12%
Pyruvate
10%
Trimetrexate
9%
Efflux Rate
8%
Clonogenic
7%
Glucose
7%
Antifolate
7%
Dihydrofolates
6%
Membrane Potential
5%
Pump
5%
Cofactor
4%
Rate Constant
3%
Pressure
2%
Reduction
2%
Medicine & Life Sciences
Folic Acid Antagonists
100%
Folic Acid
71%
Methotrexate
43%
Pyruvic Acid
9%
Trimetrexate
7%
Pyrimethamine
6%
Tetrahydrofolate Dehydrogenase
6%
Glucose
5%
Leucovorin
5%
Cell Line
5%
Cricetulus
4%
Membrane Potentials
4%
Ovary
3%
Growth
2%