Long‐Term Follow‐Up of Patients with Nonischemic Dilated Cardiomyopathy and Ventricular Tachyarrhythmias Treated with Implantable Cardioverter Defibrillators

GREGORY FAZIO, ENRICO P. VELTRI, GORDON TOMASELLI, RICHARD LEWIS, LAWRENCE S.C. GRIFFITH, THOMAS GUARNIERI

Research output: Contribution to journalArticle

41 Scopus citations

Abstract

We analyzed our 10‐year cumulative experience of 40 consecutive patients with idiopathic dilated Cardiomyopathy and associated ventricular tachyarrhythmias, treated with implantable Cardioverter defibrillators. Dilated Cardiomyopathy was defined as left ventricular ejection fraction (EF) ≤50% with no defineable etiology. Patient characteristics included: 24 male, mean age 52 years, mean EF = 33%, New York Heart Association Class I–III, presenting syndrome—cardiac arrest (n = 28), syncope/near syncope (n = 12). At 2.5 years mean follow‐up, there were 16 deaths: one operative, three sudden, two incessant ventricular tachycardia/ventricular fibrillation (VT/VF), six heart failure, and four noncardiac. The actuarial mortality at 1 and 4 years was 0% and 14% for sudden death, 11% and 34% for cardiac death. The projected mortality was 52% and 78% for same time intervals (P < 0.01). No useful baseline variable predicted who would or would not receive an ICD shock in follow‐up. ICD therapy appears effective in reducing sudden death mortality in this high risk population.

Original languageEnglish (US)
Pages (from-to)1905-1910
Number of pages6
JournalPacing and Clinical Electrophysiology
Volume14
Issue number11
DOIs
StatePublished - Nov 1991
Externally publishedYes

Keywords

  • dilated Cardiomyopathy
  • implantable Cardioverter defibrillator

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Long‐Term Follow‐Up of Patients with Nonischemic Dilated Cardiomyopathy and Ventricular Tachyarrhythmias Treated with Implantable Cardioverter Defibrillators'. Together they form a unique fingerprint.

  • Cite this