Longevity and cardiovascular disease

Clyde B. Schechter, Donna Tomlinson

Research output: Contribution to journalArticle

Abstract

Longevity and cardiovascular disease run in families. From a purely statistical perspective, factors affecting one are also likely to be associated with the other. But, beyond this, understanding how familial longevity is associated with cardiovascular mortality and the events and conditions leading to it can inform the search for heritable genetic and environmental determinants of longevity. Conversely, understanding the mechanisms and pathways that protect us from cardiovascular disease may give insight into general aging mechanisms. Accordingly, we review recent studies of the relationships among longevity, cardiovascular mortality, and cardiovascular disease risk factors. The recent literature includes studies with great methodologic advances over earlier work and leaves us better positioned to understand the many places in the causal chain leading to cardiovascular death where heritable longevity factors act. We also note the strong consistency of findings across populations in the economically developed world.

Original languageEnglish (US)
Pages (from-to)405-409
Number of pages5
JournalCurrent Cardiovascular Risk Reports
Volume2
Issue number5
DOIs
StatePublished - 2008

Fingerprint

Cardiovascular Diseases
Mortality
Population

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology

Cite this

Longevity and cardiovascular disease. / Schechter, Clyde B.; Tomlinson, Donna.

In: Current Cardiovascular Risk Reports, Vol. 2, No. 5, 2008, p. 405-409.

Research output: Contribution to journalArticle

Schechter, Clyde B. ; Tomlinson, Donna. / Longevity and cardiovascular disease. In: Current Cardiovascular Risk Reports. 2008 ; Vol. 2, No. 5. pp. 405-409.
@article{06e44e2353764eb083d09fd479d0c53b,
title = "Longevity and cardiovascular disease",
abstract = "Longevity and cardiovascular disease run in families. From a purely statistical perspective, factors affecting one are also likely to be associated with the other. But, beyond this, understanding how familial longevity is associated with cardiovascular mortality and the events and conditions leading to it can inform the search for heritable genetic and environmental determinants of longevity. Conversely, understanding the mechanisms and pathways that protect us from cardiovascular disease may give insight into general aging mechanisms. Accordingly, we review recent studies of the relationships among longevity, cardiovascular mortality, and cardiovascular disease risk factors. The recent literature includes studies with great methodologic advances over earlier work and leaves us better positioned to understand the many places in the causal chain leading to cardiovascular death where heritable longevity factors act. We also note the strong consistency of findings across populations in the economically developed world.",
author = "Schechter, {Clyde B.} and Donna Tomlinson",
year = "2008",
doi = "10.1007/s12170-008-0071-7",
language = "English (US)",
volume = "2",
pages = "405--409",
journal = "Current Cardiovascular Risk Reports",
issn = "1932-9520",
publisher = "Current Medicine Group",
number = "5",

}

TY - JOUR

T1 - Longevity and cardiovascular disease

AU - Schechter, Clyde B.

AU - Tomlinson, Donna

PY - 2008

Y1 - 2008

N2 - Longevity and cardiovascular disease run in families. From a purely statistical perspective, factors affecting one are also likely to be associated with the other. But, beyond this, understanding how familial longevity is associated with cardiovascular mortality and the events and conditions leading to it can inform the search for heritable genetic and environmental determinants of longevity. Conversely, understanding the mechanisms and pathways that protect us from cardiovascular disease may give insight into general aging mechanisms. Accordingly, we review recent studies of the relationships among longevity, cardiovascular mortality, and cardiovascular disease risk factors. The recent literature includes studies with great methodologic advances over earlier work and leaves us better positioned to understand the many places in the causal chain leading to cardiovascular death where heritable longevity factors act. We also note the strong consistency of findings across populations in the economically developed world.

AB - Longevity and cardiovascular disease run in families. From a purely statistical perspective, factors affecting one are also likely to be associated with the other. But, beyond this, understanding how familial longevity is associated with cardiovascular mortality and the events and conditions leading to it can inform the search for heritable genetic and environmental determinants of longevity. Conversely, understanding the mechanisms and pathways that protect us from cardiovascular disease may give insight into general aging mechanisms. Accordingly, we review recent studies of the relationships among longevity, cardiovascular mortality, and cardiovascular disease risk factors. The recent literature includes studies with great methodologic advances over earlier work and leaves us better positioned to understand the many places in the causal chain leading to cardiovascular death where heritable longevity factors act. We also note the strong consistency of findings across populations in the economically developed world.

UR - http://www.scopus.com/inward/record.url?scp=84873493250&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84873493250&partnerID=8YFLogxK

U2 - 10.1007/s12170-008-0071-7

DO - 10.1007/s12170-008-0071-7

M3 - Article

AN - SCOPUS:84873493250

VL - 2

SP - 405

EP - 409

JO - Current Cardiovascular Risk Reports

JF - Current Cardiovascular Risk Reports

SN - 1932-9520

IS - 5

ER -