Long-Acting β-Adrenergic Antagonists as Preparation for Surgery in Thyrotoxicosis

Paul H. Gerst, John Fildes, Peter Baylor, Joel Zonszein

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


This report describes our experience with 12 patients with thyrotoxic Graves' disease who were prepared for thyroidectomy using only a long-acting orally administered β-adrenergic blocking agent (nadolol or atenolol); iodides were not used. This form of preparation proved to be very effective, fast acting, and economical. It permitted rapid preparation of patients for surgery and resulted in excellent control of the manifestations of hyperthyroidism in the perioperative period. The surgery was relatively easy and bloodless, and there were no operative complications. We recommend that these longacting β-adrenergic blocking agents be considered as the preferred medication for the preparation of thyrotoxic patients for surgery.

Original languageEnglish (US)
Pages (from-to)838-840
Number of pages3
JournalArchives of Surgery
Issue number7
StatePublished - Jul 1986
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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