Using three sets of recombinant inbred strains (BXD, BXH, and BXJ), we found the locus controlling an antigenic substance (Sas}-1) in murine serum to be closely linked to the Chromosome-1 marker, Dip-1. This linkage was confirmed by an analysis of backcross linkage. The BXD and backcross data suggest that the gene order is Id-1 -Dip-1 -Sas-1 -Mls. Data from the three sets of RI strains and the 32 backcross mice lead to the estimate that the recombination frequency between Dip-1 and Sas-1 is 0.030 ±0.015.
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