Location of the corticospinal tract in the internal capsule at MR imaging

Akira Yagishita, Imaharu Nakano, Masaya Oda, Asao Hirano

Research output: Contribution to journalArticle

92 Citations (Scopus)

Abstract

PURPOSE: To examine whether hyperintense foci in the posterior internal capsule (IC) on T2-weighted magnetic resonance (MR) images represent fibers of the corticospinal tract (CST). MATERIALS AND METHODS: The authors reviewed MR images of 100 control subjects and 35 patients with amyotrophic lateral sclerosis (ALS) and brain specimens from seven control subjects and five ALS patients. RESULTS: In the posterior IC, the brain specimens from control subjects demonstrated a pale area with large axons and thick myelin sheaths. In five ALS patients, the brain specimens showed degeneration of the CST in the same region. MR images demonstrated abnormal hyperintensity that represented degeneration of the CST in five of 35 ALS patients. In the same region, hyperintense foci were found in the control subjects. CONCLUSION: Normal hyperintense foci in the IC represent the fibers of the CST. The presence of large fibers with thick myelin sheaths may play an important role in these signal intensity variations.

Original languageEnglish (US)
Pages (from-to)455-460
Number of pages6
JournalRadiology
Volume191
Issue number2
StatePublished - May 1994

Fingerprint

Internal Capsule
Pyramidal Tracts
Amyotrophic Lateral Sclerosis
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Myelin Sheath
Brain
Axons

Keywords

  • Amyotrophic lateral sclerosis
  • Brain, anatomy
  • Magnetic resonance (MR), tissue characterization

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Yagishita, A., Nakano, I., Oda, M., & Hirano, A. (1994). Location of the corticospinal tract in the internal capsule at MR imaging. Radiology, 191(2), 455-460.

Location of the corticospinal tract in the internal capsule at MR imaging. / Yagishita, Akira; Nakano, Imaharu; Oda, Masaya; Hirano, Asao.

In: Radiology, Vol. 191, No. 2, 05.1994, p. 455-460.

Research output: Contribution to journalArticle

Yagishita, A, Nakano, I, Oda, M & Hirano, A 1994, 'Location of the corticospinal tract in the internal capsule at MR imaging', Radiology, vol. 191, no. 2, pp. 455-460.
Yagishita A, Nakano I, Oda M, Hirano A. Location of the corticospinal tract in the internal capsule at MR imaging. Radiology. 1994 May;191(2):455-460.
Yagishita, Akira ; Nakano, Imaharu ; Oda, Masaya ; Hirano, Asao. / Location of the corticospinal tract in the internal capsule at MR imaging. In: Radiology. 1994 ; Vol. 191, No. 2. pp. 455-460.
@article{e72f50876c2e4488bac7c0896fc5feb1,
title = "Location of the corticospinal tract in the internal capsule at MR imaging",
abstract = "PURPOSE: To examine whether hyperintense foci in the posterior internal capsule (IC) on T2-weighted magnetic resonance (MR) images represent fibers of the corticospinal tract (CST). MATERIALS AND METHODS: The authors reviewed MR images of 100 control subjects and 35 patients with amyotrophic lateral sclerosis (ALS) and brain specimens from seven control subjects and five ALS patients. RESULTS: In the posterior IC, the brain specimens from control subjects demonstrated a pale area with large axons and thick myelin sheaths. In five ALS patients, the brain specimens showed degeneration of the CST in the same region. MR images demonstrated abnormal hyperintensity that represented degeneration of the CST in five of 35 ALS patients. In the same region, hyperintense foci were found in the control subjects. CONCLUSION: Normal hyperintense foci in the IC represent the fibers of the CST. The presence of large fibers with thick myelin sheaths may play an important role in these signal intensity variations.",
keywords = "Amyotrophic lateral sclerosis, Brain, anatomy, Magnetic resonance (MR), tissue characterization",
author = "Akira Yagishita and Imaharu Nakano and Masaya Oda and Asao Hirano",
year = "1994",
month = "5",
language = "English (US)",
volume = "191",
pages = "455--460",
journal = "Radiology",
issn = "0033-8419",
publisher = "Radiological Society of North America Inc.",
number = "2",

}

TY - JOUR

T1 - Location of the corticospinal tract in the internal capsule at MR imaging

AU - Yagishita, Akira

AU - Nakano, Imaharu

AU - Oda, Masaya

AU - Hirano, Asao

PY - 1994/5

Y1 - 1994/5

N2 - PURPOSE: To examine whether hyperintense foci in the posterior internal capsule (IC) on T2-weighted magnetic resonance (MR) images represent fibers of the corticospinal tract (CST). MATERIALS AND METHODS: The authors reviewed MR images of 100 control subjects and 35 patients with amyotrophic lateral sclerosis (ALS) and brain specimens from seven control subjects and five ALS patients. RESULTS: In the posterior IC, the brain specimens from control subjects demonstrated a pale area with large axons and thick myelin sheaths. In five ALS patients, the brain specimens showed degeneration of the CST in the same region. MR images demonstrated abnormal hyperintensity that represented degeneration of the CST in five of 35 ALS patients. In the same region, hyperintense foci were found in the control subjects. CONCLUSION: Normal hyperintense foci in the IC represent the fibers of the CST. The presence of large fibers with thick myelin sheaths may play an important role in these signal intensity variations.

AB - PURPOSE: To examine whether hyperintense foci in the posterior internal capsule (IC) on T2-weighted magnetic resonance (MR) images represent fibers of the corticospinal tract (CST). MATERIALS AND METHODS: The authors reviewed MR images of 100 control subjects and 35 patients with amyotrophic lateral sclerosis (ALS) and brain specimens from seven control subjects and five ALS patients. RESULTS: In the posterior IC, the brain specimens from control subjects demonstrated a pale area with large axons and thick myelin sheaths. In five ALS patients, the brain specimens showed degeneration of the CST in the same region. MR images demonstrated abnormal hyperintensity that represented degeneration of the CST in five of 35 ALS patients. In the same region, hyperintense foci were found in the control subjects. CONCLUSION: Normal hyperintense foci in the IC represent the fibers of the CST. The presence of large fibers with thick myelin sheaths may play an important role in these signal intensity variations.

KW - Amyotrophic lateral sclerosis

KW - Brain, anatomy

KW - Magnetic resonance (MR), tissue characterization

UR - http://www.scopus.com/inward/record.url?scp=0028208525&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028208525&partnerID=8YFLogxK

M3 - Article

VL - 191

SP - 455

EP - 460

JO - Radiology

JF - Radiology

SN - 0033-8419

IS - 2

ER -