Localized synchronous squamous cell carcinomas of the esophagus and hypopharynx treated with definitive concurrent chemoradiotherapy with a unified radiotherapy plan

J. B. Wallach, M. M. Rosenstein, Shalom Kalnicki

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Because of common risk factors, synchronous squamous cell carcinomas of the esophagus and head and neck are common, and their concurrent presence can significantly complicate disease eradication and survival. Here, we report the case of a patient with a history of extensive tobacco and alcohol use who was diagnosed with a localized thoracic esophageal squamous cell carcinoma, and in whom positron-emission tomography-computed tomography discovered a nearby asymptomatic localized hypopharyngeal focus that was confirmed by biopsy to also be malignant. He was treated with definitive concurrent chemoradiotherapy in a single unified radiotherapy plan, with surgery reserved for salvage treatment. He currently remains in remission without a need for surgical salvage. However, significant concern remains for both treatment failure and development of another primary because of "field cancerization."

Original languageEnglish (US)
JournalCurrent Oncology
Volume21
Issue number2
DOIs
StatePublished - 2014

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Disease Eradication
Salvage Therapy
Hypopharynx
Tobacco Use
Chemoradiotherapy
Treatment Failure
Esophagus
Squamous Cell Carcinoma
Radiotherapy
Thorax
Alcohols
Biopsy
Survival
Carcinoma, squamous cell of head and neck
Positron Emission Tomography Computed Tomography
Esophageal Squamous Cell Carcinoma

Keywords

  • Chemotherapy
  • Esophageal cancer
  • Field cancerization
  • Hypopharyngeal cancer
  • Radiotherapy
  • Synchronous squamous cell carcinomas

ASJC Scopus subject areas

  • Oncology

Cite this

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