Local anesthetic - bupivacaine increases the peritoneal transport of solutes. Part 1: In vivo study

A. Breborowicz, J. Knapowski

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

A local anesthetic - bupivacaine was used in concentration 0.25 mmol/l in the dialysis fluid during peritoneal dialysis in rabbits. Bupivacaine increased the mean peritoneal clearance of urea by 33% and of inulin by 53%. The effect of the anesthetic persisted during next exchanges, performed without the drug. Bupivacaine given intraperitoneally, did not decrease blood pressure.

Original languageEnglish (US)
Pages (from-to)221-223
Number of pages3
JournalPeritoneal Dialysis Bulletin
Volume4
Issue number4
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Nephrology

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