Liver involvement in mutliple myeloma

Roman Perez-Soler, R. Esteban, E. Allende

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

One hundred twenty-eight records of patients with multiple myeloma were reviewed to assess the incidence and manifestations of liver involvement. Histologic study of the liver was available in 21 patients. Diffuse infiltration of the liver by plasma cells was observed in 10 patients, myeloid metaplasia in four, amyloidosis in two, toxic hepatitis in two, and extrahepatic cholestasis secondary to infiltration of the peripancreatic tissue by plasma cells in one. The clinical signs of plasma cell infiltration of the liver consisted of hepatomegaly in seven patients, mild elevation of liver enzymes in five, and portal hypertension in two. Jaundice was only observed in patients with hepatitis or extrahepatic cholestasis. Liver infiltration by plasma cells did not appear to have a major prognostic significance.

Original languageEnglish (US)
Pages (from-to)25-29
Number of pages5
JournalAmerican Journal of Hematology
Volume20
Issue number1
StatePublished - 1985
Externally publishedYes

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Plasma Cells
Liver
Extrahepatic Cholestasis
Chemical and Drug Induced Liver Injury
Primary Myelofibrosis
Hepatomegaly
Portal Hypertension
Amyloidosis
Jaundice
Multiple Myeloma
Hepatitis
Incidence
Enzymes

ASJC Scopus subject areas

  • Hematology

Cite this

Perez-Soler, R., Esteban, R., & Allende, E. (1985). Liver involvement in mutliple myeloma. American Journal of Hematology, 20(1), 25-29.

Liver involvement in mutliple myeloma. / Perez-Soler, Roman; Esteban, R.; Allende, E.

In: American Journal of Hematology, Vol. 20, No. 1, 1985, p. 25-29.

Research output: Contribution to journalArticle

Perez-Soler, R, Esteban, R & Allende, E 1985, 'Liver involvement in mutliple myeloma', American Journal of Hematology, vol. 20, no. 1, pp. 25-29.
Perez-Soler, Roman ; Esteban, R. ; Allende, E. / Liver involvement in mutliple myeloma. In: American Journal of Hematology. 1985 ; Vol. 20, No. 1. pp. 25-29.
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