Abstract
The recent advances in genetic tools to manipulate Mycobacterium tuberculosis have led to the construction of defined mutants and to the study of their role in the virulence and pathogenesis of tuberculosis. The safety and vaccine potential of a few of these M. tuberculosis mutants as candidate vaccines against tuberculosis are discussed.
Original language | English (US) |
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Pages (from-to) | 955-961 |
Number of pages | 7 |
Journal | Microbes and Infection |
Volume | 7 |
Issue number | 5-6 |
DOIs | |
State | Published - May 2005 |
Keywords
- Attenuated
- Double deletion
- Pantothenate
- Tuberculosis
- Vaccine
ASJC Scopus subject areas
- Microbiology
- Immunology
- Infectious Diseases