Lipid antioxidant properties of naloxone in vitro

Kinga Koréh, Myron L. Seligman, Eugene S. Flamm, Harry B. Demopoulos

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

The results of this study indicate that naloxone diminishes ironinitiated and catalyzed peroxidation in liposomes in a concentration-dependent manner. This supports the hypothesis that the action of naloxone in vivo during amelioration of spinal cord trauma and hemorrhagic shock may substantially involve its lipid antioxidant properties.

Original languageEnglish (US)
Pages (from-to)1317-1322
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume102
Issue number4
DOIs
StatePublished - Oct 30 1981
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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