LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery

Nicole L. Levine, Yidan Zhang, Bang H. Hoang, Rui Yang, Zachary H. Jurkowski, Michael E. Roth, Jonathan B. Gill, Yungtai Lo, Ruth E. Eisenberg, Mikhail Bekarev, Richard Gorlick, David S. Geller

Research output: Contribution to journalArticle

Abstract

INTRODUCTION: The LigaSure system has been successfully used in thoracic and abdominal surgery. However, to date, its use in the resection of sarcomas has not been systematically studied. We aimed to determine whether the use of the LigaSure system reduces blood loss and blood transfusion volumes in sarcoma surgery. METHODS: One hundred forty-two consecutive patients who underwent sarcoma surgeries between July 2010 and October 2016 were included. Conventional electrocautery alone (n = 91) and with LigaSure (n = 51) were compared. Case-matched samples (n = 46) from each group were additionally compared. RESULTS: The use of the LigaSure system resulted in a significant decrease in mean intraoperative blood loss (P = 0.02) and blood transfusion volume (P = 0.04). Likewise, a significant decrease in both mean and median intraoperative blood loss (P = 0.003; P < 0.0001) was seen with LigaSure in the case-matched analysis. In the soft-tissue sarcoma subgroup, a significant decrease was observed in mean hemoglobin reduction (P = 0.03) and mean intraoperative blood loss with LigaSure (P = 0.04). No adverse perioperative complications attributed to the LigaSure system were identified. CONCLUSIONS: The LigaSure vessel sealing and dividing system is a safe and effective hemostatic tool for deep dissection in bone and soft-tissue sarcoma surgery. LEVEL OF EVIDENCE: Level III, therapeutic study.

Original languageEnglish (US)
Pages (from-to)841-847
Number of pages7
JournalThe Journal of the American Academy of Orthopaedic Surgeons
Volume27
Issue number22
DOIs
StatePublished - Nov 15 2019

Fingerprint

Blood Volume
Blood Transfusion
Sarcoma
Electrocoagulation
Hemostatics
Thoracic Surgery
Dissection
Bone and Bones
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery. / Levine, Nicole L.; Zhang, Yidan; Hoang, Bang H.; Yang, Rui; Jurkowski, Zachary H.; Roth, Michael E.; Gill, Jonathan B.; Lo, Yungtai; Eisenberg, Ruth E.; Bekarev, Mikhail; Gorlick, Richard; Geller, David S.

In: The Journal of the American Academy of Orthopaedic Surgeons, Vol. 27, No. 22, 15.11.2019, p. 841-847.

Research output: Contribution to journalArticle

Levine, NL, Zhang, Y, Hoang, BH, Yang, R, Jurkowski, ZH, Roth, ME, Gill, JB, Lo, Y, Eisenberg, RE, Bekarev, M, Gorlick, R & Geller, DS 2019, 'LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery', The Journal of the American Academy of Orthopaedic Surgeons, vol. 27, no. 22, pp. 841-847. https://doi.org/10.5435/JAAOS-D-18-00144
Levine, Nicole L. ; Zhang, Yidan ; Hoang, Bang H. ; Yang, Rui ; Jurkowski, Zachary H. ; Roth, Michael E. ; Gill, Jonathan B. ; Lo, Yungtai ; Eisenberg, Ruth E. ; Bekarev, Mikhail ; Gorlick, Richard ; Geller, David S. / LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery. In: The Journal of the American Academy of Orthopaedic Surgeons. 2019 ; Vol. 27, No. 22. pp. 841-847.
@article{5748006c234e455da58777ea5e5ae049,
title = "LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery",
abstract = "INTRODUCTION: The LigaSure system has been successfully used in thoracic and abdominal surgery. However, to date, its use in the resection of sarcomas has not been systematically studied. We aimed to determine whether the use of the LigaSure system reduces blood loss and blood transfusion volumes in sarcoma surgery. METHODS: One hundred forty-two consecutive patients who underwent sarcoma surgeries between July 2010 and October 2016 were included. Conventional electrocautery alone (n = 91) and with LigaSure (n = 51) were compared. Case-matched samples (n = 46) from each group were additionally compared. RESULTS: The use of the LigaSure system resulted in a significant decrease in mean intraoperative blood loss (P = 0.02) and blood transfusion volume (P = 0.04). Likewise, a significant decrease in both mean and median intraoperative blood loss (P = 0.003; P < 0.0001) was seen with LigaSure in the case-matched analysis. In the soft-tissue sarcoma subgroup, a significant decrease was observed in mean hemoglobin reduction (P = 0.03) and mean intraoperative blood loss with LigaSure (P = 0.04). No adverse perioperative complications attributed to the LigaSure system were identified. CONCLUSIONS: The LigaSure vessel sealing and dividing system is a safe and effective hemostatic tool for deep dissection in bone and soft-tissue sarcoma surgery. LEVEL OF EVIDENCE: Level III, therapeutic study.",
author = "Levine, {Nicole L.} and Yidan Zhang and Hoang, {Bang H.} and Rui Yang and Jurkowski, {Zachary H.} and Roth, {Michael E.} and Gill, {Jonathan B.} and Yungtai Lo and Eisenberg, {Ruth E.} and Mikhail Bekarev and Richard Gorlick and Geller, {David S.}",
year = "2019",
month = "11",
day = "15",
doi = "10.5435/JAAOS-D-18-00144",
language = "English (US)",
volume = "27",
pages = "841--847",
journal = "The Journal of the American Academy of Orthopaedic Surgeons",
issn = "1067-151X",
publisher = "American Association of Orthopaedic Surgeons",
number = "22",

}

TY - JOUR

T1 - LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery

AU - Levine, Nicole L.

AU - Zhang, Yidan

AU - Hoang, Bang H.

AU - Yang, Rui

AU - Jurkowski, Zachary H.

AU - Roth, Michael E.

AU - Gill, Jonathan B.

AU - Lo, Yungtai

AU - Eisenberg, Ruth E.

AU - Bekarev, Mikhail

AU - Gorlick, Richard

AU - Geller, David S.

PY - 2019/11/15

Y1 - 2019/11/15

N2 - INTRODUCTION: The LigaSure system has been successfully used in thoracic and abdominal surgery. However, to date, its use in the resection of sarcomas has not been systematically studied. We aimed to determine whether the use of the LigaSure system reduces blood loss and blood transfusion volumes in sarcoma surgery. METHODS: One hundred forty-two consecutive patients who underwent sarcoma surgeries between July 2010 and October 2016 were included. Conventional electrocautery alone (n = 91) and with LigaSure (n = 51) were compared. Case-matched samples (n = 46) from each group were additionally compared. RESULTS: The use of the LigaSure system resulted in a significant decrease in mean intraoperative blood loss (P = 0.02) and blood transfusion volume (P = 0.04). Likewise, a significant decrease in both mean and median intraoperative blood loss (P = 0.003; P < 0.0001) was seen with LigaSure in the case-matched analysis. In the soft-tissue sarcoma subgroup, a significant decrease was observed in mean hemoglobin reduction (P = 0.03) and mean intraoperative blood loss with LigaSure (P = 0.04). No adverse perioperative complications attributed to the LigaSure system were identified. CONCLUSIONS: The LigaSure vessel sealing and dividing system is a safe and effective hemostatic tool for deep dissection in bone and soft-tissue sarcoma surgery. LEVEL OF EVIDENCE: Level III, therapeutic study.

AB - INTRODUCTION: The LigaSure system has been successfully used in thoracic and abdominal surgery. However, to date, its use in the resection of sarcomas has not been systematically studied. We aimed to determine whether the use of the LigaSure system reduces blood loss and blood transfusion volumes in sarcoma surgery. METHODS: One hundred forty-two consecutive patients who underwent sarcoma surgeries between July 2010 and October 2016 were included. Conventional electrocautery alone (n = 91) and with LigaSure (n = 51) were compared. Case-matched samples (n = 46) from each group were additionally compared. RESULTS: The use of the LigaSure system resulted in a significant decrease in mean intraoperative blood loss (P = 0.02) and blood transfusion volume (P = 0.04). Likewise, a significant decrease in both mean and median intraoperative blood loss (P = 0.003; P < 0.0001) was seen with LigaSure in the case-matched analysis. In the soft-tissue sarcoma subgroup, a significant decrease was observed in mean hemoglobin reduction (P = 0.03) and mean intraoperative blood loss with LigaSure (P = 0.04). No adverse perioperative complications attributed to the LigaSure system were identified. CONCLUSIONS: The LigaSure vessel sealing and dividing system is a safe and effective hemostatic tool for deep dissection in bone and soft-tissue sarcoma surgery. LEVEL OF EVIDENCE: Level III, therapeutic study.

UR - http://www.scopus.com/inward/record.url?scp=85074673970&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85074673970&partnerID=8YFLogxK

U2 - 10.5435/JAAOS-D-18-00144

DO - 10.5435/JAAOS-D-18-00144

M3 - Article

C2 - 30889038

AN - SCOPUS:85074673970

VL - 27

SP - 841

EP - 847

JO - The Journal of the American Academy of Orthopaedic Surgeons

JF - The Journal of the American Academy of Orthopaedic Surgeons

SN - 1067-151X

IS - 22

ER -