Abstract
Myeloid malignancies often arise from an aging hematopoietic system and are currently incurable due to therapy-resistant, disease-reinitiating leukemic stem cells. In this issue of Cell Stem Cell, Crews et al. (2016) report RNA splice isoform signatures unique to patient-derived leukemic stem cells that constitute a therapeutic Achilles’ heel of myeloid leukemia.
Original language | English (US) |
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Pages (from-to) | 561-563 |
Number of pages | 3 |
Journal | Cell Stem Cell |
Volume | 19 |
Issue number | 5 |
DOIs | |
State | Published - Nov 3 2016 |
ASJC Scopus subject areas
- Molecular Medicine
- Genetics
- Cell Biology