Left ventricular volume determination in dogs: A comparison between conductance technique and angiocardiography

L. Tjon-a-meeuw, O. M. Hess, H. Nonogi, E. Scott Monrad, B. Leskosek, H. P. Krayenbuehl

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Left ventricular (LV) volume was determined simultaneously by monoplane cineangiocardiography and conductivity using a multielectrode conductance catheter at rest and during pressure loading in seven mongrel dogs (mean body weight 22 kg). LV volumes were calculated frame-by-frame (75 frames s-1) by angiocardiography and matched with instantaneous volumes obtained by conductivity. There was an excellent correlation between the two techniques at rest (correlation coefficient, r = 0.96) and during pressure loading (r = 0.92) when the data of each dog were pooled. The standard error of estimate of the mean angiographic volume was 4%. The slope of the regression analysis showed a small but significant (P <0.01) decrease from 0.365 at rest to 0.289 during pressure loading, whereas the intercept remained unchanged (24 versus 26 ml). Since no calibration for parallel conductivity of the surrounding tissue was performed, LV end-systolic volume was significantly over- and LV ejection fraction significantly underestimated whereas LV end-diastolic volume was estimated correctly by the conductance technique.It is concluded that LV end-diastolic volume can be determined accurately by the conductance technique in dogs. However, LV end-systolic volume is significantly over- and ejection fraction significantly under-estimated. Since there is a good correlation between angiocardiography and conductivity, exact determination Of LV volumes and ejection fraction is feasible using a correction factor. The change is slope of the regression equation between angiocardiography and conductivity suggests a change in conductivity of the surrounding tissue during pressure loading which limits the application of the conductance catheter to stable haemodynamic situations or calls for repeated calibrations by an independent technique during acute interventions.

Original languageEnglish (US)
Pages (from-to)1018-1026
Number of pages9
JournalEuropean Heart Journal
Volume9
Issue number9
StatePublished - Sep 1988
Externally publishedYes

Fingerprint

Angiocardiography
Conductance
Stroke Volume
Dogs
Conductivity
Catheters
Pressure
Calibration
Tissue
Hemodynamics
Regression analysis
Slope
Dog
Body Weight
Regression Analysis
Intercept
Standard error
Correlation coefficient
Acute
Instantaneous

Keywords

  • Angiocardiography
  • Calcium agonist
  • Conductance catheter
  • Left ventricular volume determination

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Tjon-a-meeuw, L., Hess, O. M., Nonogi, H., Monrad, E. S., Leskosek, B., & Krayenbuehl, H. P. (1988). Left ventricular volume determination in dogs: A comparison between conductance technique and angiocardiography. European Heart Journal, 9(9), 1018-1026.

Left ventricular volume determination in dogs : A comparison between conductance technique and angiocardiography. / Tjon-a-meeuw, L.; Hess, O. M.; Nonogi, H.; Monrad, E. Scott; Leskosek, B.; Krayenbuehl, H. P.

In: European Heart Journal, Vol. 9, No. 9, 09.1988, p. 1018-1026.

Research output: Contribution to journalArticle

Tjon-a-meeuw, L, Hess, OM, Nonogi, H, Monrad, ES, Leskosek, B & Krayenbuehl, HP 1988, 'Left ventricular volume determination in dogs: A comparison between conductance technique and angiocardiography', European Heart Journal, vol. 9, no. 9, pp. 1018-1026.
Tjon-a-meeuw, L. ; Hess, O. M. ; Nonogi, H. ; Monrad, E. Scott ; Leskosek, B. ; Krayenbuehl, H. P. / Left ventricular volume determination in dogs : A comparison between conductance technique and angiocardiography. In: European Heart Journal. 1988 ; Vol. 9, No. 9. pp. 1018-1026.
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