TY - JOUR
T1 - Left ventricular assist devices and bleeding
T2 - Adding insult to injury
AU - Goldstein, Daniel J.
AU - Beauford, Robert B.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2003/6/1
Y1 - 2003/6/1
N2 - Bleeding is the most common postoperative complication after implantation of left ventricular assist devices, necessitating reoperation in up to 60% of recipients. The implications of massive blood transfusions are great and include infection, pulmonary insufficiency, increased costs, right heart failure, allosensitization, and viral transmission, some of which can prove fatal or preclude transplantation. Preoperative evaluation and preparation are essential, intraoperative hemostasis is imperative, and "shotgun" product replacement should be avoided. Adherence to protocols emphasizing "hemostatic readiness" could reduce the incidence of bleeding complications that pervade left ventricular assist device therapy and potentially improve current successes in bridging to transplantation.
AB - Bleeding is the most common postoperative complication after implantation of left ventricular assist devices, necessitating reoperation in up to 60% of recipients. The implications of massive blood transfusions are great and include infection, pulmonary insufficiency, increased costs, right heart failure, allosensitization, and viral transmission, some of which can prove fatal or preclude transplantation. Preoperative evaluation and preparation are essential, intraoperative hemostasis is imperative, and "shotgun" product replacement should be avoided. Adherence to protocols emphasizing "hemostatic readiness" could reduce the incidence of bleeding complications that pervade left ventricular assist device therapy and potentially improve current successes in bridging to transplantation.
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U2 - 10.1016/S0003-4975(03)00478-8
DO - 10.1016/S0003-4975(03)00478-8
M3 - Article
C2 - 12820734
AN - SCOPUS:0037636659
SN - 0003-4975
VL - 75
SP - S42-S47
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 6 SUPPL.
ER -