Lead poisoning

A disease for the next millennium

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

The decline in the prevalence of childhood lead poisoning is a public health success story. However, nearly a million preschool-aged children in the United States alone have elevated BPb levels. Toxicity correlates with BPb concentrations and progresses from biochemical and subclinical abnormalities at levels around 10 μg/dL to coma and death at levels over 100 μg/dL. Treatment consists of the elimination of exposure, interruption of the pathway into the child, modification of diet to ensure adequate essential metal intake (calcium, iron), and on occasion, chelation therapy. The identification of children with the most lead poisoning depends on screening for exposure (questionnaire) or evidence of increased absorption (BPb test). Follow-up is crucial to maximize the effectiveness of any intervention.

Original languageEnglish (US)
Pages (from-to)62-70
Number of pages9
JournalCurrent Problems in Pediatrics
Volume30
Issue number3
DOIs
StatePublished - 2000

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Lead Poisoning
Chelation Therapy
Diet Therapy
Preschool Children
Coma
Iron
Public Health
Metals
Calcium
Therapeutics
Surveys and Questionnaires

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Lead poisoning : A disease for the next millennium. / Markowitz, Morri E.

In: Current Problems in Pediatrics, Vol. 30, No. 3, 2000, p. 62-70.

Research output: Contribution to journalArticle

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