Laser welding with albumin-based solder

Experimental full-tubed skin graft urethroplasty

Andrew J. Kirsch, David T. Chang, Mark L. Kayton, Steven K. Libutti, Michael R. Treat, Terry W. Hensle

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background and Objective: Fistula and stricture formation at the site of sutured anastomoses are frequent complications of major urethroplasty. We performed urethroplasty using laser-welded skin tube grafts in the hope that in addition to being free of suture holes, grafts would be as strong as or stronger than sutured controls. Study Design/Material and Methods: Scrotal skin was harvested from each of 11 rabbits and fashioned into tubes 3-4 cm in length using either conventional suture techniques or laser welding. Welding was performed using an 808-nm diode laser and a dye enhanced solder composed of albumin and sodium hyaluronate. Laser power density was 15.9 watts/cm 2. For each graft, leak pressure, and urethroplasty time (tube creation and anastomosis to native urethra) were measured. Results: Urethroplasty time was significantly shorter and initial leak pressures were seven times greater in the laser-welded group. Conclusions: The near-uniform occurrence of strictures in both groups suggests that the rabbit is not an ideal model for free tube graft urethroplasty. However, our data indicate that laser welding with albumin-based solder, when used in the appropriate setting, may offer the potential for the rapid creation of watertight grafts in reconstructive urology.

Original languageEnglish (US)
Pages (from-to)225-230
Number of pages6
JournalLasers in Surgery and Medicine
Volume18
Issue number3
DOIs
StatePublished - 1996
Externally publishedYes

Fingerprint

Welding
Albumins
Lasers
Transplants
Skin
Pathologic Constriction
Rabbits
Suture Techniques
Pressure
Semiconductor Lasers
Urology
Urethra
Hyaluronic Acid
Sutures
Fistula
Coloring Agents

Keywords

  • glue
  • reconstruction
  • urology

ASJC Scopus subject areas

  • Surgery

Cite this

Laser welding with albumin-based solder : Experimental full-tubed skin graft urethroplasty. / Kirsch, Andrew J.; Chang, David T.; Kayton, Mark L.; Libutti, Steven K.; Treat, Michael R.; Hensle, Terry W.

In: Lasers in Surgery and Medicine, Vol. 18, No. 3, 1996, p. 225-230.

Research output: Contribution to journalArticle

Kirsch, Andrew J. ; Chang, David T. ; Kayton, Mark L. ; Libutti, Steven K. ; Treat, Michael R. ; Hensle, Terry W. / Laser welding with albumin-based solder : Experimental full-tubed skin graft urethroplasty. In: Lasers in Surgery and Medicine. 1996 ; Vol. 18, No. 3. pp. 225-230.
@article{dcfe088f09b54355bfdc13659c2044cd,
title = "Laser welding with albumin-based solder: Experimental full-tubed skin graft urethroplasty",
abstract = "Background and Objective: Fistula and stricture formation at the site of sutured anastomoses are frequent complications of major urethroplasty. We performed urethroplasty using laser-welded skin tube grafts in the hope that in addition to being free of suture holes, grafts would be as strong as or stronger than sutured controls. Study Design/Material and Methods: Scrotal skin was harvested from each of 11 rabbits and fashioned into tubes 3-4 cm in length using either conventional suture techniques or laser welding. Welding was performed using an 808-nm diode laser and a dye enhanced solder composed of albumin and sodium hyaluronate. Laser power density was 15.9 watts/cm 2. For each graft, leak pressure, and urethroplasty time (tube creation and anastomosis to native urethra) were measured. Results: Urethroplasty time was significantly shorter and initial leak pressures were seven times greater in the laser-welded group. Conclusions: The near-uniform occurrence of strictures in both groups suggests that the rabbit is not an ideal model for free tube graft urethroplasty. However, our data indicate that laser welding with albumin-based solder, when used in the appropriate setting, may offer the potential for the rapid creation of watertight grafts in reconstructive urology.",
keywords = "glue, reconstruction, urology",
author = "Kirsch, {Andrew J.} and Chang, {David T.} and Kayton, {Mark L.} and Libutti, {Steven K.} and Treat, {Michael R.} and Hensle, {Terry W.}",
year = "1996",
doi = "10.1002/(SICI)1096-9101(1996)18:3<225::AID-LSM2>3.0.CO;2-U",
language = "English (US)",
volume = "18",
pages = "225--230",
journal = "Lasers in Surgery and Medicine",
issn = "0196-8092",
publisher = "Wiley-Liss Inc.",
number = "3",

}

TY - JOUR

T1 - Laser welding with albumin-based solder

T2 - Experimental full-tubed skin graft urethroplasty

AU - Kirsch, Andrew J.

AU - Chang, David T.

AU - Kayton, Mark L.

AU - Libutti, Steven K.

AU - Treat, Michael R.

AU - Hensle, Terry W.

PY - 1996

Y1 - 1996

N2 - Background and Objective: Fistula and stricture formation at the site of sutured anastomoses are frequent complications of major urethroplasty. We performed urethroplasty using laser-welded skin tube grafts in the hope that in addition to being free of suture holes, grafts would be as strong as or stronger than sutured controls. Study Design/Material and Methods: Scrotal skin was harvested from each of 11 rabbits and fashioned into tubes 3-4 cm in length using either conventional suture techniques or laser welding. Welding was performed using an 808-nm diode laser and a dye enhanced solder composed of albumin and sodium hyaluronate. Laser power density was 15.9 watts/cm 2. For each graft, leak pressure, and urethroplasty time (tube creation and anastomosis to native urethra) were measured. Results: Urethroplasty time was significantly shorter and initial leak pressures were seven times greater in the laser-welded group. Conclusions: The near-uniform occurrence of strictures in both groups suggests that the rabbit is not an ideal model for free tube graft urethroplasty. However, our data indicate that laser welding with albumin-based solder, when used in the appropriate setting, may offer the potential for the rapid creation of watertight grafts in reconstructive urology.

AB - Background and Objective: Fistula and stricture formation at the site of sutured anastomoses are frequent complications of major urethroplasty. We performed urethroplasty using laser-welded skin tube grafts in the hope that in addition to being free of suture holes, grafts would be as strong as or stronger than sutured controls. Study Design/Material and Methods: Scrotal skin was harvested from each of 11 rabbits and fashioned into tubes 3-4 cm in length using either conventional suture techniques or laser welding. Welding was performed using an 808-nm diode laser and a dye enhanced solder composed of albumin and sodium hyaluronate. Laser power density was 15.9 watts/cm 2. For each graft, leak pressure, and urethroplasty time (tube creation and anastomosis to native urethra) were measured. Results: Urethroplasty time was significantly shorter and initial leak pressures were seven times greater in the laser-welded group. Conclusions: The near-uniform occurrence of strictures in both groups suggests that the rabbit is not an ideal model for free tube graft urethroplasty. However, our data indicate that laser welding with albumin-based solder, when used in the appropriate setting, may offer the potential for the rapid creation of watertight grafts in reconstructive urology.

KW - glue

KW - reconstruction

KW - urology

UR - http://www.scopus.com/inward/record.url?scp=0029863219&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029863219&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1096-9101(1996)18:3<225::AID-LSM2>3.0.CO;2-U

DO - 10.1002/(SICI)1096-9101(1996)18:3<225::AID-LSM2>3.0.CO;2-U

M3 - Article

VL - 18

SP - 225

EP - 230

JO - Lasers in Surgery and Medicine

JF - Lasers in Surgery and Medicine

SN - 0196-8092

IS - 3

ER -