Laryngotracheal Recurrent Papillomatosis: A Case Study and Survey of Surgical and Systemic Management

Michela Borrelli; Tasha Nasrollahi; Jonathan Raskin; Sana Khan; Ronda E. Alexander

doi:10.1177/01455613221128714

Laryngotracheal Recurrent Papillomatosis: A Case Study and Survey of Surgical and Systemic Management

Michela Borrelli, Tasha Nasrollahi, Jonathan Raskin, Sana Khan, Ronda E. Alexander

Research output: Contribution to journal › Article › peer-review

Abstract

This case report presents a 72-year-old man with longstanding recurrent respiratory papillomatosis (RRP). He has undergone multiple procedures for the condition, including an apparent urgent surgical airway followed by tracheoplasty repair. Modern management of complicated RRP should include both local debulking and systemic approaches. Systemic bevacizumab (Avastin) has shown some initial success as an effective treatment option, in addition to other medications such as pembrolizumab. Other future care strategies may include an HPV vaccination and other adjuvants; vaccination has been reported to have the possibility of drastically reducing the incidence of RRP.

Original language	English (US)
Pages (from-to)	47S-51S
Journal	Ear, Nose and Throat Journal
Volume	101
Issue number	10_suppl
DOIs	https://doi.org/10.1177/01455613221128714
State	Published - Dec 2022
Externally published	Yes

Keywords

dysphonia
dysplasia
laryngotracheal recurrent papillomatosis
squamous papilloma
vocal cord
vocal fold

ASJC Scopus subject areas

Otorhinolaryngology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/01455613221128714

Cite this

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title = "Laryngotracheal Recurrent Papillomatosis: A Case Study and Survey of Surgical and Systemic Management",

abstract = "This case report presents a 72-year-old man with longstanding recurrent respiratory papillomatosis (RRP). He has undergone multiple procedures for the condition, including an apparent urgent surgical airway followed by tracheoplasty repair. Modern management of complicated RRP should include both local debulking and systemic approaches. Systemic bevacizumab (Avastin) has shown some initial success as an effective treatment option, in addition to other medications such as pembrolizumab. Other future care strategies may include an HPV vaccination and other adjuvants; vaccination has been reported to have the possibility of drastically reducing the incidence of RRP.",

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AU - Borrelli, Michela

AU - Nasrollahi, Tasha

AU - Raskin, Jonathan

AU - Khan, Sana

AU - Alexander, Ronda E.

N1 - Publisher Copyright: © The Author(s) 2022.

PY - 2022/12

Y1 - 2022/12

N2 - This case report presents a 72-year-old man with longstanding recurrent respiratory papillomatosis (RRP). He has undergone multiple procedures for the condition, including an apparent urgent surgical airway followed by tracheoplasty repair. Modern management of complicated RRP should include both local debulking and systemic approaches. Systemic bevacizumab (Avastin) has shown some initial success as an effective treatment option, in addition to other medications such as pembrolizumab. Other future care strategies may include an HPV vaccination and other adjuvants; vaccination has been reported to have the possibility of drastically reducing the incidence of RRP.

AB - This case report presents a 72-year-old man with longstanding recurrent respiratory papillomatosis (RRP). He has undergone multiple procedures for the condition, including an apparent urgent surgical airway followed by tracheoplasty repair. Modern management of complicated RRP should include both local debulking and systemic approaches. Systemic bevacizumab (Avastin) has shown some initial success as an effective treatment option, in addition to other medications such as pembrolizumab. Other future care strategies may include an HPV vaccination and other adjuvants; vaccination has been reported to have the possibility of drastically reducing the incidence of RRP.

KW - dysphonia

KW - dysplasia

KW - laryngotracheal recurrent papillomatosis

KW - squamous papilloma

KW - vocal cord

KW - vocal fold

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Laryngotracheal Recurrent Papillomatosis: A Case Study and Survey of Surgical and Systemic Management

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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