Large fetal sacrococcygeal teratomas: Could early delivery improve outcome?

Cynthia J. Holcroft, Karin J. Blakemore, Edith D. Gurewitsch, Rita W. Driggers, Frances J. Northington, Anne C. Fischer

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Objective: To determine if gestational age (GA) at delivery or tumor size impacts outcome in neonates with very large sacrococcygeal teratomas (SCTs). Methods: Retrospective chart review from 1990 to 2006 of live-born infants with very large SCTs, defined as diameters exceeding 10 cm. Data analyzed using the independent t test and Fisher's exact test, with p values <0.05 considered significant. Results: Nine infants with very large SCTs were identified. Six of the 9 infants survived, 4 of whom had evidence of early hydrops. Mean GA of survivors was 32.2 ± 3.7 versus 31.7 ± 0.6 weeks in nonsurvivors (p = 0.85). Infants with the largest SCTs did not survive. Conclusion: Risks of preterm delivery must be weighed against complications from further enlargement of very large SCTs and against the risks of in utero intervention.

Original languageEnglish (US)
Pages (from-to)55-60
Number of pages6
JournalFetal Diagnosis and Therapy
Volume24
Issue number1
DOIs
StatePublished - Jul 1 2008
Externally publishedYes

Keywords

  • Prematurity
  • Sacrococcygeal teratoma
  • Survival

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Embryology
  • Radiology Nuclear Medicine and imaging
  • Obstetrics and Gynecology

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    Holcroft, C. J., Blakemore, K. J., Gurewitsch, E. D., Driggers, R. W., Northington, F. J., & Fischer, A. C. (2008). Large fetal sacrococcygeal teratomas: Could early delivery improve outcome? Fetal Diagnosis and Therapy, 24(1), 55-60. https://doi.org/10.1159/000132408