Just how stable are escape rhythms after atrioventricular junction ablation?

Rishi Arora, Erica Spatz, Pugazhendhi Vijayaraman, Michael Rosengarten, Jay N. Gross, Soo G. Kim, John Devens Fisher, Kevin J. Ferrick

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Atrioventricular (AV) node ablation with implantation of a permanent pacemaker is an established mode of therapy in the treatment of atrial fibrillation. However, concern exists regarding subsequent dependency on an entirely paced rhythm and the possible sequela of unheralded pacemaker failure. Data regarding escape rhythm lability, an important feature of pacemaker dependency, are limited. Aims and Methods: The purpose of this study was twofold: (1) to determine the characteristics of escape rhythms at predefined serial time intervals following AV node ablation and pacemaker implantation, and (2) to identify risk factors predictive of unstable escape rhythms. Patients undergoing AV node ablation and pacemaker implantation were assessed for the presence or absence of an escape rhythm during pacemaker interrogation at five predetermined serial time points. Baseline demographics and comorbid conditions were evaluated as potential predictors of those with labile escape rhythms. Results: Seventy-nine percent of the 96 patients studied had an underlying escape rhythm (≥30 beats per minute) immediately postablation. Although the percentage of patients with an escape rhythm increased at each follow-up interval, the number of patients who consistently demonstrated an escape rhythm declined with each follow-up, with 28% of patients lacking an escape rhythm at some time point, i.e., labile escape rhythm. There were no significant predictors of a labile escape rhythm. Conclusion: Among patients who have undergone AV node ablation and pacemaker implantation, 72% have a stable escape rhythm over time, but others are at risk for pacemaker dependency, as predicted by an underlying absent or labile escape rhythm.

Original languageEnglish (US)
Pages (from-to)939-944
Number of pages6
JournalPACE - Pacing and Clinical Electrophysiology
Volume33
Issue number8
DOIs
StatePublished - Aug 2010

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Atrioventricular Node
Atrial Fibrillation
Demography
Therapeutics

Keywords

  • atrioventricular node ablation
  • escape rhythm
  • pacemaker dependency

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Just how stable are escape rhythms after atrioventricular junction ablation? / Arora, Rishi; Spatz, Erica; Vijayaraman, Pugazhendhi; Rosengarten, Michael; Gross, Jay N.; Kim, Soo G.; Fisher, John Devens; Ferrick, Kevin J.

In: PACE - Pacing and Clinical Electrophysiology, Vol. 33, No. 8, 08.2010, p. 939-944.

Research output: Contribution to journalArticle

Arora, Rishi ; Spatz, Erica ; Vijayaraman, Pugazhendhi ; Rosengarten, Michael ; Gross, Jay N. ; Kim, Soo G. ; Fisher, John Devens ; Ferrick, Kevin J. / Just how stable are escape rhythms after atrioventricular junction ablation?. In: PACE - Pacing and Clinical Electrophysiology. 2010 ; Vol. 33, No. 8. pp. 939-944.
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abstract = "Background: Atrioventricular (AV) node ablation with implantation of a permanent pacemaker is an established mode of therapy in the treatment of atrial fibrillation. However, concern exists regarding subsequent dependency on an entirely paced rhythm and the possible sequela of unheralded pacemaker failure. Data regarding escape rhythm lability, an important feature of pacemaker dependency, are limited. Aims and Methods: The purpose of this study was twofold: (1) to determine the characteristics of escape rhythms at predefined serial time intervals following AV node ablation and pacemaker implantation, and (2) to identify risk factors predictive of unstable escape rhythms. Patients undergoing AV node ablation and pacemaker implantation were assessed for the presence or absence of an escape rhythm during pacemaker interrogation at five predetermined serial time points. Baseline demographics and comorbid conditions were evaluated as potential predictors of those with labile escape rhythms. Results: Seventy-nine percent of the 96 patients studied had an underlying escape rhythm (≥30 beats per minute) immediately postablation. Although the percentage of patients with an escape rhythm increased at each follow-up interval, the number of patients who consistently demonstrated an escape rhythm declined with each follow-up, with 28{\%} of patients lacking an escape rhythm at some time point, i.e., labile escape rhythm. There were no significant predictors of a labile escape rhythm. Conclusion: Among patients who have undergone AV node ablation and pacemaker implantation, 72{\%} have a stable escape rhythm over time, but others are at risk for pacemaker dependency, as predicted by an underlying absent or labile escape rhythm.",
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