Isolated central nervous system granulomatosis resembling sarcoidosis

S. C. Lee, J. Spencer, J. Rumberg, D. W. Dickson

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Isolated central nervous system (CNS) granulomatosis resembling sarcoidosis occurred in a 30-year-old woman who had amenorrhea, ataxia, and obstructive hydrocephalus, and a 9-year course of progressive neurological deterioration with recurrent bouts of diabetes insipidus. Lamellar and nodular meningeal hyalinosis resembling amyloid was noted on an initial brain biopsy. At autopsy, the brain had a non-necrotizing granulomatous meningitis and ventriculitis, most prominent at the base of the brain, including the third ventricle and the hypothalamus, but there were no systemic granulomas.

Original languageEnglish (US)
Pages (from-to)356-358
Number of pages3
JournalJournal of Neurology
Volume236
Issue number6
DOIs
StatePublished - Sep 1989

Fingerprint

Sarcoidosis
Central Nervous System
Brain
Diabetes Insipidus
Third Ventricle
Amenorrhea
Ataxia
Hydrocephalus
Granuloma
Meningitis
Amyloid
Hypothalamus
Autopsy
Biopsy

Keywords

  • Amyloid
  • Isolated
  • Neurosarcoidosis
  • Pulmonary hyalinizing granuloma

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Lee, S. C., Spencer, J., Rumberg, J., & Dickson, D. W. (1989). Isolated central nervous system granulomatosis resembling sarcoidosis. Journal of Neurology, 236(6), 356-358. https://doi.org/10.1007/BF00314381

Isolated central nervous system granulomatosis resembling sarcoidosis. / Lee, S. C.; Spencer, J.; Rumberg, J.; Dickson, D. W.

In: Journal of Neurology, Vol. 236, No. 6, 09.1989, p. 356-358.

Research output: Contribution to journalArticle

Lee, SC, Spencer, J, Rumberg, J & Dickson, DW 1989, 'Isolated central nervous system granulomatosis resembling sarcoidosis', Journal of Neurology, vol. 236, no. 6, pp. 356-358. https://doi.org/10.1007/BF00314381
Lee, S. C. ; Spencer, J. ; Rumberg, J. ; Dickson, D. W. / Isolated central nervous system granulomatosis resembling sarcoidosis. In: Journal of Neurology. 1989 ; Vol. 236, No. 6. pp. 356-358.
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