Is vitamin supplementation appropriate in the healthy old?

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

PURPOSE OF REVIEW: Vitamin supplements are used by large numbers of older adults. Although vitamins serve several functions in the body, the benefits or harm of routine supplementation are far from clear. Data from studies over the last decade are reviewed to enable an understanding. RECENT FINDINGS: Summarized data from studies conducted over the last few years, pertinent to the use of vitamins, as multivitamin combinations and as individual vitamins specifically A, D, E, C, and the B group, are presented. This review targets the benefits and harm of multivitamins when used to lower the risk of cancer, cardiovascular and cerebrovascular disease, visual disorders (e.g., cataracts and age-related macular degeneration), and bone disease. The effects of vitamins on total mortality are discussed. In addition, isolated or multiple vitamin deficiencies, their predisposing settings and manifestations from mild-to-life-threatening illness are discussed. SUMMARY: Data from studies demonstrate considerable variations, most confirming little to no benefit following supplementation in healthy adults. However, clear roles exist for vitamin supplementation in states of deficiency and in subgroups of older adults at high risk for deficiency of specific or multiple vitamins. In these settings, vitamin supplements help prevent or correct deficiency and related manifestations.

Original languageEnglish (US)
Pages (from-to)143-152
Number of pages10
JournalCurrent Opinion in Gastroenterology
Volume31
Issue number2
DOIs
StatePublished - Mar 13 2015

Fingerprint

Vitamins
Avitaminosis
Cerebrovascular Disorders
Dilatation and Curettage
Bone Diseases
Vision Disorders
Macular Degeneration
Cataract
Cardiovascular Diseases
Mortality
Neoplasms

Keywords

  • healthy diet versus vitamins
  • multivitamin use in older adults
  • vascular disease and mortality
  • vitamin benefits for cancer
  • vitamin use in subgroups with deficiency
  • vitamins and adverse effects

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Is vitamin supplementation appropriate in the healthy old? / Dharmarajan, Thiruvinvamalai S.

In: Current Opinion in Gastroenterology, Vol. 31, No. 2, 13.03.2015, p. 143-152.

Research output: Contribution to journalArticle

@article{ba7f78c2c11747ecba6d03a2511cf9a4,
title = "Is vitamin supplementation appropriate in the healthy old?",
abstract = "PURPOSE OF REVIEW: Vitamin supplements are used by large numbers of older adults. Although vitamins serve several functions in the body, the benefits or harm of routine supplementation are far from clear. Data from studies over the last decade are reviewed to enable an understanding. RECENT FINDINGS: Summarized data from studies conducted over the last few years, pertinent to the use of vitamins, as multivitamin combinations and as individual vitamins specifically A, D, E, C, and the B group, are presented. This review targets the benefits and harm of multivitamins when used to lower the risk of cancer, cardiovascular and cerebrovascular disease, visual disorders (e.g., cataracts and age-related macular degeneration), and bone disease. The effects of vitamins on total mortality are discussed. In addition, isolated or multiple vitamin deficiencies, their predisposing settings and manifestations from mild-to-life-threatening illness are discussed. SUMMARY: Data from studies demonstrate considerable variations, most confirming little to no benefit following supplementation in healthy adults. However, clear roles exist for vitamin supplementation in states of deficiency and in subgroups of older adults at high risk for deficiency of specific or multiple vitamins. In these settings, vitamin supplements help prevent or correct deficiency and related manifestations.",
keywords = "healthy diet versus vitamins, multivitamin use in older adults, vascular disease and mortality, vitamin benefits for cancer, vitamin use in subgroups with deficiency, vitamins and adverse effects",
author = "Dharmarajan, {Thiruvinvamalai S.}",
year = "2015",
month = "3",
day = "13",
doi = "10.1097/MOG.0000000000000150",
language = "English (US)",
volume = "31",
pages = "143--152",
journal = "Current Opinion in Gastroenterology",
issn = "0267-1379",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Is vitamin supplementation appropriate in the healthy old?

AU - Dharmarajan, Thiruvinvamalai S.

PY - 2015/3/13

Y1 - 2015/3/13

N2 - PURPOSE OF REVIEW: Vitamin supplements are used by large numbers of older adults. Although vitamins serve several functions in the body, the benefits or harm of routine supplementation are far from clear. Data from studies over the last decade are reviewed to enable an understanding. RECENT FINDINGS: Summarized data from studies conducted over the last few years, pertinent to the use of vitamins, as multivitamin combinations and as individual vitamins specifically A, D, E, C, and the B group, are presented. This review targets the benefits and harm of multivitamins when used to lower the risk of cancer, cardiovascular and cerebrovascular disease, visual disorders (e.g., cataracts and age-related macular degeneration), and bone disease. The effects of vitamins on total mortality are discussed. In addition, isolated or multiple vitamin deficiencies, their predisposing settings and manifestations from mild-to-life-threatening illness are discussed. SUMMARY: Data from studies demonstrate considerable variations, most confirming little to no benefit following supplementation in healthy adults. However, clear roles exist for vitamin supplementation in states of deficiency and in subgroups of older adults at high risk for deficiency of specific or multiple vitamins. In these settings, vitamin supplements help prevent or correct deficiency and related manifestations.

AB - PURPOSE OF REVIEW: Vitamin supplements are used by large numbers of older adults. Although vitamins serve several functions in the body, the benefits or harm of routine supplementation are far from clear. Data from studies over the last decade are reviewed to enable an understanding. RECENT FINDINGS: Summarized data from studies conducted over the last few years, pertinent to the use of vitamins, as multivitamin combinations and as individual vitamins specifically A, D, E, C, and the B group, are presented. This review targets the benefits and harm of multivitamins when used to lower the risk of cancer, cardiovascular and cerebrovascular disease, visual disorders (e.g., cataracts and age-related macular degeneration), and bone disease. The effects of vitamins on total mortality are discussed. In addition, isolated or multiple vitamin deficiencies, their predisposing settings and manifestations from mild-to-life-threatening illness are discussed. SUMMARY: Data from studies demonstrate considerable variations, most confirming little to no benefit following supplementation in healthy adults. However, clear roles exist for vitamin supplementation in states of deficiency and in subgroups of older adults at high risk for deficiency of specific or multiple vitamins. In these settings, vitamin supplements help prevent or correct deficiency and related manifestations.

KW - healthy diet versus vitamins

KW - multivitamin use in older adults

KW - vascular disease and mortality

KW - vitamin benefits for cancer

KW - vitamin use in subgroups with deficiency

KW - vitamins and adverse effects

UR - http://www.scopus.com/inward/record.url?scp=84922708096&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84922708096&partnerID=8YFLogxK

U2 - 10.1097/MOG.0000000000000150

DO - 10.1097/MOG.0000000000000150

M3 - Article

C2 - 25635666

AN - SCOPUS:84922708096

VL - 31

SP - 143

EP - 152

JO - Current Opinion in Gastroenterology

JF - Current Opinion in Gastroenterology

SN - 0267-1379

IS - 2

ER -