Is Papillomavirus Detectable in the Plume of Laser-Treated Laryngeal Papilloma?

Allan L. Abramson, Teresa P. Dilorenzo, Bettie M. Steinberg

Research output: Contribution to journalArticle

42 Scopus citations


• The carbon dioxide laser is widely used for the vaporization of lesions in patients with laryngeal papillomatosis. In this study, the smoke plume resulting from the laser treatment of laryngeal papillomas was analyzed for the presence of human papillomavirus DNA. Plumes were collected with a suction tip and trapped in phosphate-buffered saline. The aspirates were then analyzed for the presence of human papillomavirus DNA by Southern blot hybridization. Human papillomavirus DNA cannot be detected in the smoke plume from vaporization of laryngeal papillomas unless direct suction contact is made with the papilloma tissue during surgery. The implications of these findings are discussed. (Arch Otolaryngol Head Neck Surg. 1990;116:604-607).

Original languageEnglish (US)
Pages (from-to)604-607
Number of pages4
JournalArchives of Otolaryngology--Head and Neck Surgery
Issue number5
StatePublished - May 1990


ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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