Is obsessive-compulsive disorder an anxiety disorder?

Jennifer A. Bartz, Eric Hollander

Research output: Contribution to journalArticle

124 Citations (Scopus)

Abstract

Obsessive-compulsive disorder (OCD) is classified as an anxiety disorder in the DSM-IV-TR [American Psychiatric Association, 2000. Diagnostic and statistical manual of mental disorders, Fourth ed., rev. Washington, DC: Author]; however, the notion of a spectrum of obsessive-compulsive (OC) related disorders that is comprised of such disparate disorders as OCD, body dysmorphic disorder, certain eating disorders, pathological gambling, and autism, is gaining acceptance. The fact that these disorders share obsessive-compulsive features and evidence similarities in patient characteristics, course, comorbidity, neurobiology, and treatment response raises the question of whether OCD is best conceptualized as an anxiety or an OC spectrum disorder. This article reviews evidence from comorbidity and family studies, as well as biological evidence related to neurocircuitry, neurotransmitter function, and pharmacologic treatment response that bear on this question. The implications of removing OCD from the anxiety disorders category and moving it to an OC spectrum disorders category, as is being proposed for the DSM-V, is discussed.

Original languageEnglish (US)
Pages (from-to)338-352
Number of pages15
JournalProgress in Neuro-Psychopharmacology and Biological Psychiatry
Volume30
Issue number3
DOIs
StatePublished - May 2006
Externally publishedYes

Fingerprint

Obsessive-Compulsive Disorder
Anxiety Disorders
Diagnostic and Statistical Manual of Mental Disorders
Comorbidity
Body Dysmorphic Disorders
Gambling
Neurobiology
Autistic Disorder
Neurotransmitter Agents
Anxiety
Therapeutics

Keywords

  • Anxiety disorder
  • Nosology
  • Obsessive-compulsive disorder (OCD)
  • Obsessive-compulsive spectrum

ASJC Scopus subject areas

  • Biological Psychiatry
  • Pharmacology

Cite this

Is obsessive-compulsive disorder an anxiety disorder? / Bartz, Jennifer A.; Hollander, Eric.

In: Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 30, No. 3, 05.2006, p. 338-352.

Research output: Contribution to journalArticle

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