Is fructose malabsorption a cause of irritable bowel syndrome?

James J. DiNicolantonio, Sean C. Lucan

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Irritable Bowel Syndrome (IBS) is a condition that may be marked by abdominal pain, bloating, fullness, indigestion, belching, constipation and/or diarrhea. IBS symptoms can result from malabsorption of fructose. Fructose is a monosaccharide found naturally in small quantities in fruits and some vegetables, and in much larger quantities in industrially manufactured sweets with added sugars (e.g. sucrose and high fructose corn syrup). Fructose malabsorption leads to osmotic diarrhea as well as gas and bloating due to fermentation in the colon. A low-fructose diet has been found to improve IBS symptoms in some patients. This paper discusses the prevalence of fructose malabsorption and considers fructose ingestion as a possible cause of--and fructose restriction as a possible dietary treatment for--IBS.

Original languageEnglish (US)
Pages (from-to)295-297
Number of pages3
JournalMedical Hypotheses
Volume85
Issue number3
DOIs
StatePublished - Sep 1 2015

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Irritable Bowel Syndrome
Fructose
Diarrhea
Eructation
Oil and Gas Fields
Monosaccharides
Dyspepsia
Constipation
Vegetables
Abdominal Pain
Fermentation
Sucrose
Fruit
Colon
Eating
Diet

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Is fructose malabsorption a cause of irritable bowel syndrome? / DiNicolantonio, James J.; Lucan, Sean C.

In: Medical Hypotheses, Vol. 85, No. 3, 01.09.2015, p. 295-297.

Research output: Contribution to journalArticle

DiNicolantonio, James J. ; Lucan, Sean C. / Is fructose malabsorption a cause of irritable bowel syndrome?. In: Medical Hypotheses. 2015 ; Vol. 85, No. 3. pp. 295-297.
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