Ion Channel Diseases: an Update for 2016

Gordon F. Tomaselli; Andreas S. Barth

doi:10.1007/s11936-016-0442-1

Ion Channel Diseases: an Update for 2016

Gordon F. Tomaselli, Andreas S. Barth

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

Ion channelopathies are a frequent cause of sudden cardiac death (SCD) in patients with structurally normal hearts. These are generally Mendelian inherited electrical disorders with variable penetrance and expressivity. The ability to predict the development of life threatening arrhythmias in these patients is challenging. This chapter will present an update on the genetics, the role of genetic testing, and management of the inherited cardiac channelopathies with a focus on the relatively more common syndromes associated with an increased risk of SCD.

Original language	English (US)
Article number	21
Pages (from-to)	1-21
Number of pages	21
Journal	Current Treatment Options in Cardiovascular Medicine
Volume	18
Issue number	3
DOIs	https://doi.org/10.1007/s11936-016-0442-1
State	Published - Mar 1 2016
Externally published	Yes

Keywords

Arrhythmia
Ion channel diseases
Sudden cardiac death

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1007/s11936-016-0442-1

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abstract = "Ion channelopathies are a frequent cause of sudden cardiac death (SCD) in patients with structurally normal hearts. These are generally Mendelian inherited electrical disorders with variable penetrance and expressivity. The ability to predict the development of life threatening arrhythmias in these patients is challenging. This chapter will present an update on the genetics, the role of genetic testing, and management of the inherited cardiac channelopathies with a focus on the relatively more common syndromes associated with an increased risk of SCD.",

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N2 - Ion channelopathies are a frequent cause of sudden cardiac death (SCD) in patients with structurally normal hearts. These are generally Mendelian inherited electrical disorders with variable penetrance and expressivity. The ability to predict the development of life threatening arrhythmias in these patients is challenging. This chapter will present an update on the genetics, the role of genetic testing, and management of the inherited cardiac channelopathies with a focus on the relatively more common syndromes associated with an increased risk of SCD.

AB - Ion channelopathies are a frequent cause of sudden cardiac death (SCD) in patients with structurally normal hearts. These are generally Mendelian inherited electrical disorders with variable penetrance and expressivity. The ability to predict the development of life threatening arrhythmias in these patients is challenging. This chapter will present an update on the genetics, the role of genetic testing, and management of the inherited cardiac channelopathies with a focus on the relatively more common syndromes associated with an increased risk of SCD.

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Ion Channel Diseases: an Update for 2016

Abstract

Keywords

ASJC Scopus subject areas

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