Intravital imaging of cell movement in tumours

John Condeelis; Jeffrey E. Segall

doi:10.1038/nrc1231

Intravital imaging of cell movement in tumours

John Condeelis, Jeffrey E. Segall

Research output: Contribution to journal › Review article › peer-review

771 Scopus citations

Abstract

Metastasis is the cause of death for patients with many types of cancer, but the process of tumour cell dissemination is poorly understood. As primary tumours are three-dimensional, departure of cells from primary tumours has been difficult to study. Multiphoton microscopy has been developed for in vivo imaging and, using this technique, we are beginning to understand how invasive tumour cells move.

Original language	English (US)
Pages (from-to)	921-930
Number of pages	10
Journal	Nature Reviews Cancer
Volume	3
Issue number	12
DOIs	https://doi.org/10.1038/nrc1231
State	Published - Dec 2003

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/nrc1231

Cite this

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abstract = "Metastasis is the cause of death for patients with many types of cancer, but the process of tumour cell dissemination is poorly understood. As primary tumours are three-dimensional, departure of cells from primary tumours has been difficult to study. Multiphoton microscopy has been developed for in vivo imaging and, using this technique, we are beginning to understand how invasive tumour cells move.",

author = "John Condeelis and Segall, {Jeffrey E.}",

note = "Funding Information: We apologize to those authors whose work we could not cite directly due to space limitations. The authors acknowledge the contributions of current and former laboratory members to the work discussed in this review. The authors{\textquoteright} research summarized here has been supported by the National Institutes of Health, and the US Department of Defense Breast Cancer Research Program.",

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AU - Segall, Jeffrey E.

N1 - Funding Information: We apologize to those authors whose work we could not cite directly due to space limitations. The authors acknowledge the contributions of current and former laboratory members to the work discussed in this review. The authors’ research summarized here has been supported by the National Institutes of Health, and the US Department of Defense Breast Cancer Research Program.

PY - 2003/12

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N2 - Metastasis is the cause of death for patients with many types of cancer, but the process of tumour cell dissemination is poorly understood. As primary tumours are three-dimensional, departure of cells from primary tumours has been difficult to study. Multiphoton microscopy has been developed for in vivo imaging and, using this technique, we are beginning to understand how invasive tumour cells move.

AB - Metastasis is the cause of death for patients with many types of cancer, but the process of tumour cell dissemination is poorly understood. As primary tumours are three-dimensional, departure of cells from primary tumours has been difficult to study. Multiphoton microscopy has been developed for in vivo imaging and, using this technique, we are beginning to understand how invasive tumour cells move.

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Intravital imaging of cell movement in tumours

Abstract

ASJC Scopus subject areas

UN SDGs

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