Intravenous leiomyomatosis with intracardiac extension: a single-institution experience

Micheal J. Worley, Anate Aelion, Thomas A. Caputo, Kenneth C. Kent, Arash Salemi, Karl H. Krieger, Michael J. Goldstein, Dennis Yi-Shin Kuo, Brian M. Slomovitz

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Objective: The aim of this study was to outline the surgical management and outcomes for patients diagnosed with intravenous leiomyomatosis with intracardiac extension at a single institution. Study Design: This was a retrospective review of patients diagnosed with intravenous leiomyomatosis with intracardiac extension between 2002-2008. Results: Four patients were identified. The surgical approach in 3 (75%) patients was a single-stage operation. Four (100%) patients presented with cardiac symptoms: 3 (75%) with syncope and 1 (25%) with an abnormal electrocardiogram. Mean age at presentation was 48 years (range, 42-58 years). Complete resection of tumor was obtained in 1 (25%) patient and 3 (75%) patients experienced incomplete resection. Mean follow-up, including surveillance imaging, was 25.5 months (range, 8-57 months) and all 4 patients (100%) are currently free of recurrence. Conclusion: Surgical excision remains an effective therapy for treating patients with benign metastasizing leiomyomatosis. Incomplete surgical resection may result in favorable response.

Original languageEnglish (US)
JournalAmerican Journal of Obstetrics and Gynecology
Volume201
Issue number6
DOIs
StatePublished - Dec 2009
Externally publishedYes

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Leiomyomatosis
Syncope
Electrocardiography

Keywords

  • cardiac mass
  • fibroid
  • intravenous leiomyomatosis

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Worley, M. J., Aelion, A., Caputo, T. A., Kent, K. C., Salemi, A., Krieger, K. H., ... Slomovitz, B. M. (2009). Intravenous leiomyomatosis with intracardiac extension: a single-institution experience. American Journal of Obstetrics and Gynecology, 201(6). https://doi.org/10.1016/j.ajog.2009.06.037

Intravenous leiomyomatosis with intracardiac extension : a single-institution experience. / Worley, Micheal J.; Aelion, Anate; Caputo, Thomas A.; Kent, Kenneth C.; Salemi, Arash; Krieger, Karl H.; Goldstein, Michael J.; Kuo, Dennis Yi-Shin; Slomovitz, Brian M.

In: American Journal of Obstetrics and Gynecology, Vol. 201, No. 6, 12.2009.

Research output: Contribution to journalArticle

Worley, MJ, Aelion, A, Caputo, TA, Kent, KC, Salemi, A, Krieger, KH, Goldstein, MJ, Kuo, DY-S & Slomovitz, BM 2009, 'Intravenous leiomyomatosis with intracardiac extension: a single-institution experience', American Journal of Obstetrics and Gynecology, vol. 201, no. 6. https://doi.org/10.1016/j.ajog.2009.06.037
Worley, Micheal J. ; Aelion, Anate ; Caputo, Thomas A. ; Kent, Kenneth C. ; Salemi, Arash ; Krieger, Karl H. ; Goldstein, Michael J. ; Kuo, Dennis Yi-Shin ; Slomovitz, Brian M. / Intravenous leiomyomatosis with intracardiac extension : a single-institution experience. In: American Journal of Obstetrics and Gynecology. 2009 ; Vol. 201, No. 6.
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