TY - JOUR
T1 - Intravenous caffeine versus intravenous ketorolac for the management of moderate to severe migraine headache
AU - Baratloo, Alireza
AU - Bafarani, Sara Arab
AU - Forouzanfar, Mohammad Mehdi
AU - Hashemi, Behrooz
AU - Friedman, Benjamin Wolkin
AU - Abdalvand, Ali
N1 - Publisher Copyright:
© 2016, Bangladesh Pharmacological Society. All rights reserved.
PY - 2016
Y1 - 2016
N2 - The aim of this study was to determine if intravenous caffeine is as effective as intravenous ketorolac for the treatment of moderate to severe migraine headaches. Eligible patients randomly received 60 mg caffeine citrate or 60 mg ketorolac infused intravenously. Their pain score were measured at baseline, one hour and two hours after infusion. Therapeutic success was defined as decreasing of at least 3 points on the pain score. In total 110 patients were enrolled (75.5% women). Therapeutic success after 60 min was achieved by 63.6% of patients in the caffeine and 70.1% of patients in the ketorolac group (p = 0.23). After 120 min, 87.3% of the caffeine group and 83.6% of the ketorolac group achieved therapeutic success (p = 0.49). In this multi-center, randomized double blind study, intravenous caffeine was as effective as intravenous ketorolac for first line abortive management of acute migraine.
AB - The aim of this study was to determine if intravenous caffeine is as effective as intravenous ketorolac for the treatment of moderate to severe migraine headaches. Eligible patients randomly received 60 mg caffeine citrate or 60 mg ketorolac infused intravenously. Their pain score were measured at baseline, one hour and two hours after infusion. Therapeutic success was defined as decreasing of at least 3 points on the pain score. In total 110 patients were enrolled (75.5% women). Therapeutic success after 60 min was achieved by 63.6% of patients in the caffeine and 70.1% of patients in the ketorolac group (p = 0.23). After 120 min, 87.3% of the caffeine group and 83.6% of the ketorolac group achieved therapeutic success (p = 0.49). In this multi-center, randomized double blind study, intravenous caffeine was as effective as intravenous ketorolac for first line abortive management of acute migraine.
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U2 - 10.3329/bjp.v11i2.26333
DO - 10.3329/bjp.v11i2.26333
M3 - Article
AN - SCOPUS:84977558483
SN - 1991-007X
VL - 11
SP - 428
EP - 432
JO - Bangladesh Journal of Pharmacology
JF - Bangladesh Journal of Pharmacology
IS - 2
ER -