Abstract
Background: Hepatitis A is a common, self-limited disease transmitted by fecal-oral contamination. Case: A 23-year-old woman, para 2-0-0-2, developed hepatitis A at 20 weeks' gestation. At 27 weeks, ultrasound revealed polyhydramnios and fetal ascites. Hepatitis A immunoglobulin M antibody in fetal blood obtained by funipuncture confirmed acute hepatitis A infection in the fetus. Polyhydramnios and ascites persisted until 35 weeks, when the fetus developed ultrasound signs of meconium peritonitis, and delivery was accomplished uneventfully. Meconium peritonitis was diagnosed in the neonatal period and treated surgically. Conclusion: To our knowledge, this is the first report of intrauterine transmission of hepatitis A. The disease presented with fetal ascites and was confirmed by positive fetal blood serology.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 690-691 |
| Number of pages | 2 |
| Journal | Obstetrics and Gynecology |
| Volume | 88 |
| Issue number | 4 II SUPPL. |
| DOIs | |
| State | Published - Oct 1996 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Obstetrics and Gynecology
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Intrauterine transmission of hepatitis A virus. / Leikin, Enid; Lysikiewicz, Andrzej; Garry, David; Tejani, Nergesh.
In: Obstetrics and Gynecology, Vol. 88, No. 4 II SUPPL., 10.1996, p. 690-691.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intrauterine transmission of hepatitis A virus
AU - Leikin, Enid
AU - Lysikiewicz, Andrzej
AU - Garry, David
AU - Tejani, Nergesh
PY - 1996/10
Y1 - 1996/10
N2 - Background: Hepatitis A is a common, self-limited disease transmitted by fecal-oral contamination. Case: A 23-year-old woman, para 2-0-0-2, developed hepatitis A at 20 weeks' gestation. At 27 weeks, ultrasound revealed polyhydramnios and fetal ascites. Hepatitis A immunoglobulin M antibody in fetal blood obtained by funipuncture confirmed acute hepatitis A infection in the fetus. Polyhydramnios and ascites persisted until 35 weeks, when the fetus developed ultrasound signs of meconium peritonitis, and delivery was accomplished uneventfully. Meconium peritonitis was diagnosed in the neonatal period and treated surgically. Conclusion: To our knowledge, this is the first report of intrauterine transmission of hepatitis A. The disease presented with fetal ascites and was confirmed by positive fetal blood serology.
AB - Background: Hepatitis A is a common, self-limited disease transmitted by fecal-oral contamination. Case: A 23-year-old woman, para 2-0-0-2, developed hepatitis A at 20 weeks' gestation. At 27 weeks, ultrasound revealed polyhydramnios and fetal ascites. Hepatitis A immunoglobulin M antibody in fetal blood obtained by funipuncture confirmed acute hepatitis A infection in the fetus. Polyhydramnios and ascites persisted until 35 weeks, when the fetus developed ultrasound signs of meconium peritonitis, and delivery was accomplished uneventfully. Meconium peritonitis was diagnosed in the neonatal period and treated surgically. Conclusion: To our knowledge, this is the first report of intrauterine transmission of hepatitis A. The disease presented with fetal ascites and was confirmed by positive fetal blood serology.
UR - http://www.scopus.com/inward/record.url?scp=0029777449&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029777449&partnerID=8YFLogxK
U2 - 10.1016/0029-7844(96)00259-1
DO - 10.1016/0029-7844(96)00259-1
M3 - Article
C2 - 8841254
AN - SCOPUS:0029777449
VL - 88
SP - 690
EP - 691
JO - Obstetrics and Gynecology
JF - Obstetrics and Gynecology
SN - 0029-7844
IS - 4 II SUPPL.
ER -