Intrauterine transmission of hepatitis A virus

Enid Leikin; Andrzej Lysikiewicz; David Garry; Nergesh Tejani

doi:10.1016/0029-7844(96)00259-1

Intrauterine transmission of hepatitis A virus

Enid Leikin, Andrzej Lysikiewicz, David Garry, Nergesh Tejani

Obstetrics & Gynecology and Women's Health

Research output: Contribution to journal › Article

58 Scopus citations

Abstract

Background: Hepatitis A is a common, self-limited disease transmitted by fecal-oral contamination. Case: A 23-year-old woman, para 2-0-0-2, developed hepatitis A at 20 weeks' gestation. At 27 weeks, ultrasound revealed polyhydramnios and fetal ascites. Hepatitis A immunoglobulin M antibody in fetal blood obtained by funipuncture confirmed acute hepatitis A infection in the fetus. Polyhydramnios and ascites persisted until 35 weeks, when the fetus developed ultrasound signs of meconium peritonitis, and delivery was accomplished uneventfully. Meconium peritonitis was diagnosed in the neonatal period and treated surgically. Conclusion: To our knowledge, this is the first report of intrauterine transmission of hepatitis A. The disease presented with fetal ascites and was confirmed by positive fetal blood serology.

Original language	English (US)
Pages (from-to)	690-691
Number of pages	2
Journal	Obstetrics and gynecology
Volume	88
Issue number	4 II SUPPL.
DOIs	https://doi.org/10.1016/0029-7844(96)00259-1
Publication status	Published - Oct 1996

Fingerprint

ASJC Scopus subject areas

Obstetrics and Gynecology

Cite this

Leikin, E., Lysikiewicz, A., Garry, D., & Tejani, N. (1996). Intrauterine transmission of hepatitis A virus. Obstetrics and gynecology, 88(4 II SUPPL.), 690-691. https://doi.org/10.1016/0029-7844(96)00259-1

@article{79e8bce536f641cdbe5d4ef314ab22cf,

title = "Intrauterine transmission of hepatitis A virus",

abstract = "Background: Hepatitis A is a common, self-limited disease transmitted by fecal-oral contamination. Case: A 23-year-old woman, para 2-0-0-2, developed hepatitis A at 20 weeks' gestation. At 27 weeks, ultrasound revealed polyhydramnios and fetal ascites. Hepatitis A immunoglobulin M antibody in fetal blood obtained by funipuncture confirmed acute hepatitis A infection in the fetus. Polyhydramnios and ascites persisted until 35 weeks, when the fetus developed ultrasound signs of meconium peritonitis, and delivery was accomplished uneventfully. Meconium peritonitis was diagnosed in the neonatal period and treated surgically. Conclusion: To our knowledge, this is the first report of intrauterine transmission of hepatitis A. The disease presented with fetal ascites and was confirmed by positive fetal blood serology.",

author = "Enid Leikin and Andrzej Lysikiewicz and David Garry and Nergesh Tejani",

year = "1996",

month = "10",

doi = "10.1016/0029-7844(96)00259-1",

language = "English (US)",

volume = "88",

pages = "690--691",

journal = "Obstetrics and Gynecology",

issn = "0029-7844",

publisher = "Lippincott Williams and Wilkins",

number = "4 II SUPPL.",

}

TY - JOUR

T1 - Intrauterine transmission of hepatitis A virus

AU - Leikin, Enid

AU - Lysikiewicz, Andrzej

AU - Garry, David

AU - Tejani, Nergesh

PY - 1996/10

Y1 - 1996/10

N2 - Background: Hepatitis A is a common, self-limited disease transmitted by fecal-oral contamination. Case: A 23-year-old woman, para 2-0-0-2, developed hepatitis A at 20 weeks' gestation. At 27 weeks, ultrasound revealed polyhydramnios and fetal ascites. Hepatitis A immunoglobulin M antibody in fetal blood obtained by funipuncture confirmed acute hepatitis A infection in the fetus. Polyhydramnios and ascites persisted until 35 weeks, when the fetus developed ultrasound signs of meconium peritonitis, and delivery was accomplished uneventfully. Meconium peritonitis was diagnosed in the neonatal period and treated surgically. Conclusion: To our knowledge, this is the first report of intrauterine transmission of hepatitis A. The disease presented with fetal ascites and was confirmed by positive fetal blood serology.

AB - Background: Hepatitis A is a common, self-limited disease transmitted by fecal-oral contamination. Case: A 23-year-old woman, para 2-0-0-2, developed hepatitis A at 20 weeks' gestation. At 27 weeks, ultrasound revealed polyhydramnios and fetal ascites. Hepatitis A immunoglobulin M antibody in fetal blood obtained by funipuncture confirmed acute hepatitis A infection in the fetus. Polyhydramnios and ascites persisted until 35 weeks, when the fetus developed ultrasound signs of meconium peritonitis, and delivery was accomplished uneventfully. Meconium peritonitis was diagnosed in the neonatal period and treated surgically. Conclusion: To our knowledge, this is the first report of intrauterine transmission of hepatitis A. The disease presented with fetal ascites and was confirmed by positive fetal blood serology.

UR - http://www.scopus.com/inward/record.url?scp=0029777449&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029777449&partnerID=8YFLogxK

U2 - 10.1016/0029-7844(96)00259-1

DO - 10.1016/0029-7844(96)00259-1

M3 - Article

C2 - 8841254

AN - SCOPUS:0029777449

VL - 88

SP - 690

EP - 691

JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

SN - 0029-7844

IS - 4 II SUPPL.

ER -

Access to Document

10.1016/0029-7844(96)00259-1