Intramedullary spinal cord metastasis - Pathologic findings in five autopsy cases

Y. Hashizume, A. Hirano

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

This report describes the pathologic findings in five autopsy cases with intramedullary spinal cord metastasis. In an autopsy series over a 30-year period, the incidence of intramedullary metastasis among the metastatic tumors to the spine was 3.5%, and the incidence among the central nervous system (CNS) metastasis was 4.2%. Primary site of tumor was the lung in four cases, and cancer of the thyroid was suspected in one case. On transverse section, the tumor was located mainly in the ventral part of the posterior horn and the medial part of the lateral column. Involvement was focal extending over one to six segments. In two cases, secondary hemorrhage occurred in the posterior horn or the posterior column. In three cases, central ischemic infarction was noted cephalad and caudad to the tumor metastasis. The mode of tumor spread to the spinal cord is not clear, but the autopsy findings in our series suggest that intramedullary tumor may result from hematogenous spread via the arterial circulation.

Original languageEnglish (US)
Pages (from-to)214-218
Number of pages5
JournalActa Neuropathologica
Volume61
Issue number3-4
DOIs
StatePublished - Sep 1983

Fingerprint

Autopsy
Spinal Cord
Neoplasm Metastasis
Neoplasms
Horns
Incidence
Thyroid Neoplasms
Infarction
Spine
Central Nervous System
Hemorrhage
Lung

Keywords

  • Hematogenous spread
  • Intramedullary metastasis
  • Spinal cord

ASJC Scopus subject areas

  • Neuroscience(all)
  • Pathology and Forensic Medicine
  • Clinical Neurology

Cite this

Intramedullary spinal cord metastasis - Pathologic findings in five autopsy cases. / Hashizume, Y.; Hirano, A.

In: Acta Neuropathologica, Vol. 61, No. 3-4, 09.1983, p. 214-218.

Research output: Contribution to journalArticle

Hashizume, Y. ; Hirano, A. / Intramedullary spinal cord metastasis - Pathologic findings in five autopsy cases. In: Acta Neuropathologica. 1983 ; Vol. 61, No. 3-4. pp. 214-218.
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