Intracranial oculomotor nerve paresis with anisocoria and pupillary parasympathetic hypersensitivity

Thomas L. Slamovits, Neil R. Miller, Ronald M. Burde

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Three patients developed anisocoria as a result of third nerve palsies caused by intracranial lesions: two in the cavernous sinus and one in the mesencephalon. Pharmacologic testing using low concentration pilocarpine showed apparent preganglionic parasympathetic supersensitivity of the abnormal pupil. These findings are compatible with the existence of a proposed direct pathway from the midbrain to the eye, without synapse at the ciliary ganglion. Cholinergic hypersensitivity can occur, not only with postciliary ganglionic but also with preciliary ganglionic parasympathetic lesions.

Original languageEnglish (US)
Pages (from-to)401-406
Number of pages6
JournalAmerican Journal of Ophthalmology
Volume104
Issue number4
StatePublished - Oct 15 1987
Externally publishedYes

Fingerprint

Anisocoria
Oculomotor Nerve
Paresis
Mesencephalon
Hypersensitivity
Parasympathetic Ganglia
Oculomotor Nerve Diseases
Cavernous Sinus
Pilocarpine
Pupil
Synapses
Cholinergic Agents

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Intracranial oculomotor nerve paresis with anisocoria and pupillary parasympathetic hypersensitivity. / Slamovits, Thomas L.; Miller, Neil R.; Burde, Ronald M.

In: American Journal of Ophthalmology, Vol. 104, No. 4, 15.10.1987, p. 401-406.

Research output: Contribution to journalArticle

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