Abstract
Brain metastases are among the most common and feared complications of cancer. Over the past decades, advances in our understanding of cancer biology along with refinements of existing treatment modalities have begun to challenge therapeutic nihilism. Surgical resection and radiation remain mainstays of treatment, but debate exists over their appropriate use and timing. In addition to outlining the epidemiology, presentation, and work-up of the patient with brain metastases, this chapter explores these controversies and outlines a rational approach to management.
Original language | English (US) |
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Title of host publication | Neuro-oncology |
Subtitle of host publication | First Edition |
Publisher | Blackwell Publishing Ltd |
Pages | 177-190 |
Number of pages | 14 |
ISBN (Print) | 9780470655757 |
DOIs | |
State | Published - Feb 29 2012 |
Keywords
- Anticonvulsants
- Brain metastases
- Corticosteroids
- Molecularly targeted agents
- Stereotactic radiosurgery (SRS)
- Whole-brain radiation (WBRT)
ASJC Scopus subject areas
- Neuroscience(all)
- Medicine(all)