Intra-Amniotic Pressure Reduction in Twin-Twin Transfusion Syndrome

David Garry, Andrzej Lysikiewicz, Jonathan Mays, Joseph Canterino, Nergesh Tejani

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Abstract

OBJECTIVE: Our purpose was to measure intra-amniotic pressure before and after decompression amniocentesis in twin-twin transfusion syndrome. STUDY DESIGN: Intra-amniotic pressures were measured during decompression amniocentesis on 18 occasions in 5 pregnancies complicated by twin-twin transfusion syndrome. The intra-amniotic pressure was determined with a water manometer before and after removal of amniotic fluid. For comparison, intra-amniotic pressure was determined in 10 uncomplicated gestations. RESULTS: Initial intra-amniotic pressures in twin-twin transfusion gestations (mean, 17.2 ± 5.2 cm H2O; range, 5.5 to 33.0 cm H2O) were higher than those of the uncomplicated gestations (mean, 8.4 ± 3.3 cm H2O; range, 3.5 to 13.5 cm H2O; p < 0.002). Intra-amniotic pressures following therapeutic amniocentesis (mean, 10.9 ± 5.1 cm H2O; range, 3.5 to 23.0 cm H2O) were not different from those of the uncomplicated gestations (p = 0.16). CONCLUSION: The intra-amniotic pressure in twin-twin transfusion gestations is higher than that of the uncomplicated gestation. Decompression amniocentesis reduces intra-amniotic pressure to that of the uncomplicated gestation.

Original languageEnglish (US)
Pages (from-to)284-286
Number of pages3
JournalJournal of Perinatology
Volume18
Issue number4
Publication statusPublished - Jul 1 1998

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Garry, D., Lysikiewicz, A., Mays, J., Canterino, J., & Tejani, N. (1998). Intra-Amniotic Pressure Reduction in Twin-Twin Transfusion Syndrome. Journal of Perinatology, 18(4), 284-286.