Intestinal microbiota and the efficacy of fecal microbiota transplantation in gastrointestinal disease

Research output: Contribution to journalReview article

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Abstract

Fecal microbiota transplantation (FMT) refers to the infusion of a fecal suspension from a healthy person into the gastrointestinal (GI) tract of another person to cure a specific disease. FMT is by no means a new therapeutic modality, although it was only relatively recently that stool was shown to be a biologically active, complex mixture of living organisms with great therapeutic potential for recurrent Clostridium difficile infection and perhaps other GI and non-GI disorders. The published revelations about the human microbiome are bringing the strength of science to clinical observation and enhancing the understanding of not only disease but also how much of a person's daily function and health depends on the microorganisms living in intimate relationship with each cell in the body.

Original languageEnglish (US)
Pages (from-to)230-237
Number of pages8
JournalGastroenterology and Hepatology
Volume10
Issue number4
StatePublished - Apr 2014

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Keywords

  • Clostridium difficile
  • Fecal microbiota transplantation
  • Inflammatory bowel disease
  • Irritable bowel syndrome

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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