TY - JOUR
T1 - Interferon induced Autoimmune Thyroid Disease (AITD)
T2 - A model for human autoimmunity
AU - Oppenheim, Yael
AU - Ban, Yoshiyuki
AU - Tomer, Yaron
N1 - Funding Information:
This work was supported in part by grants DK61659 & DK58072 from NIDDKD (to YT).
PY - 2004/7
Y1 - 2004/7
N2 - Interferon (IFN) α treatment for various conditions has been associated with thyroid autoimmunity. The incidence of interferon induced thyroid autoimmunity has been reported to range from 2.5% to 42%, possibly depending upon dose and duration of medical therapy and patient characteristics. It is not known whether IFN-α initiates autoimmune thyroid disease (AITD) or simply exacerbates AITD in individuals with subclinical AITD.
AB - Interferon (IFN) α treatment for various conditions has been associated with thyroid autoimmunity. The incidence of interferon induced thyroid autoimmunity has been reported to range from 2.5% to 42%, possibly depending upon dose and duration of medical therapy and patient characteristics. It is not known whether IFN-α initiates autoimmune thyroid disease (AITD) or simply exacerbates AITD in individuals with subclinical AITD.
KW - Hepatitis C
KW - Interferon-α
KW - Thyroid autoantibody
KW - Thyroid autoimmunity
UR - http://www.scopus.com/inward/record.url?scp=3342986718&partnerID=8YFLogxK
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U2 - 10.1016/j.autrev.2004.03.003
DO - 10.1016/j.autrev.2004.03.003
M3 - Review article
C2 - 15288006
AN - SCOPUS:3342986718
SN - 1568-9972
VL - 3
SP - 388
EP - 393
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
IS - 5
ER -
