Interferon induced Autoimmune Thyroid Disease (AITD): A model for human autoimmunity

Yael Oppenheim, Yoshiyuki Ban, Yaron Tomer

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations


Interferon (IFN) α treatment for various conditions has been associated with thyroid autoimmunity. The incidence of interferon induced thyroid autoimmunity has been reported to range from 2.5% to 42%, possibly depending upon dose and duration of medical therapy and patient characteristics. It is not known whether IFN-α initiates autoimmune thyroid disease (AITD) or simply exacerbates AITD in individuals with subclinical AITD.

Original languageEnglish (US)
Pages (from-to)388-393
Number of pages6
JournalAutoimmunity Reviews
Issue number5
StatePublished - Jul 1 2004
Externally publishedYes


  • Hepatitis C
  • Interferon-α
  • Thyroid autoantibody
  • Thyroid autoimmunity

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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